DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30091 and Egfbp2

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_034245.3	Gene:	Egfbp2 / 13647	MGIID:	95292	Length:	261	Species:	Mus musculus

Alignment Length:	277	Identity:	77/277 - (27%)
Similarity:	118/277 - (42%)	Gaps:	45/277 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WVVLFAWMLTAGRGSARLLDEDCGVPMQLIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITN 69
            |.::....|:.|       ..|...|:|  .::|||.:..:...||...:....|.||||.::..
Mouse     2 WFLILFLALSLG-------GIDAAPPLQ--SRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDR 57

  Fly    70 KFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLL---ATGEH-----NHPHEIYNVERVYIHDSFA 126
            .:|||||||.         ..|..|.||...|.   .:.:|     :.||..:|:..:.:.....
Mouse    58 NWVLTAAHCY---------VDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPP 113

  Fly   127 IQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWG--VTGNGKMSNNLQM 189
            ..::.||:.||||.|.......:||:. |...:.||.:..:    |.|||  .....:..::||.
Mouse   114 GADFSNDLMLLRLSKPADITDVVKPIA-LPTKEPKPGSKCL----ASGWGSITPTRWQKPDDLQC 173

  Fly   190 VKIYRIDRKMCEAAFWYTFDYPMFCAG-TAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTG 253
            |.|..:..:.|...:.......|.||| ...|:|||:.||||||    :.|||.:    |..|.|
Mouse   174 VFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPL----ICDGILQ----GTTSYG 230

  Fly   254 TEDCRGFG---MYTDVM 267
            ...|...|   :||:::
Mouse   231 PVPCGKPGVPAIYTNLI 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	71/246 (29%)
		Tryp_SPc	37..276	CDD:238113	71/245 (29%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Egfbp2	NP_034245.3	Tryp_SPc	24..253	CDD:214473	71/246 (29%)
Egfbp2	NP_034245.3	Tryp_SPc	25..256	CDD:238113	71/245 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910