DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30091 and CG43124

DIOPT Version :9

Sequence 1:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001247345.1	Gene:	CG43124 / 12798282	FlyBaseID:	FBgn0262587	Length:	245	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	76/297 - (25%)
Similarity:	117/297 - (39%)	Gaps:	85/297 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WVVLFAWMLTAGRGSARLLDEDCGVPMQLIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITN 69
            |:|| ..:|...:|||:.|:|||...|:.|        .|....||:|.|.::.:.||.|::|.|
  Fly     6 WIVL-CIVLMFYQGSAQTLEEDCVDHMERI--------NGSSYAPWLAEILSDSKVICAGALINN 61

  Fly    70 KFVLTAAHCMCTDEECIVKYTQLTVTLGVYHLLATGEHNHPHEIYNVERVYIHDSFAIQNYRNDI 134
            .:|||||.|...:|       :|||.||      :|..:..:|.:.|.:.|...:....|..|::
  Fly    62 LYVLTAASCFKENE-------KLTVRLG------SGYFDKSYENFRVTKAYFWMTHFPANNTNNL 113

  Fly   135 ALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMVKIYRIDRKM 199
            .:.|||..:.:|..|:|:||.                          |...:|.:...:.|..:
  Fly   114 CIFRLQTEVEFKTHIRPMCIT--------------------------KSPKSLGLATTFEIINE- 151

  Fly   200 CEAAFWYTFDYPMFC-------------------AGTAVGRDTCKRDSGGPLYIHMLFDGIKRAT 245
             :...||      ||                   .....|....:..|.||      |.|:.|..
  Fly   152 -KPKMWY------FCKNIKGLFCKYVFGENEEKWQSKPTGSPWTETISNGP------FKGLVRYG 203

  Fly   246 QLGIVSTGTEDCRGFGMYTDVMGHIDFIERIVLDADI 282
            .|......|.|    .:|.:||.||::|.:|.|:.||
  Fly   204 ILSYRDNKTYD----EVYINVMSHINWIAQISLEIDI 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	58/255 (23%)
		Tryp_SPc	37..276	CDD:238113	59/257 (23%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
CG43124	NP_001247345.1	Tryp_SPc	41..>133	CDD:304450	33/104 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010