Protein Alignment Erasp and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_725487.1
• Gene: Erasp / 246448
• FlyBaseID: FBgn0050090
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 89/276 - (32%)
• Similarity: 128/276 - (46%)
• Gaps: 46/276 - (16%)

  Fly    13 IGVLCSLGNGEYLEPRCGLTANTIAFKIIGGRDAIINSNPWMAYIHSSVKLICGGTLITQRFVLT 77
            |.:.||         .|||.|.|  .:|:||..|..:..||...:|.....|||||||..::|||
Human   310 ISLQCS---------HCGLRAMT--GRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLT 363

  Fly    78 AAHC-------VNEGSAVKVRLGEYDDTATEDCNSKICIPRAEEHDVDMAFRHGKFSEIKNLNDI 135
            ||||       |.||  .||..|      |.:.:.   :|.|.  .:.....:..:::.::..||
Human   364 AAHCFFVTREKVLEG--WKVYAG------TSNLHQ---LPEAA--SIAEIIINSNYTDEEDDYDI 415

  Fly   136 ALLRLAKFVTFKAHISPICIILGTSKRELVDSIEWFVATGWGETR--THRTRGVLQITQLQRYNS 198
            ||:||:|.:|..|||.|.|:.:......|.::. |.  ||:|:||  ..:|...|:..|:...:.
Human   416 ALMRLSKPLTLSAHIHPACLPMHGQTFSLNETC-WI--TGFGKTRETDDKTSPFLREVQVNLIDF 477

  Fly   199 SQCMQAL--GRLVQQNQICAGRL--GSDTCNGDSGGPLFQTVRHMDKMRPVQFGVVSYGS--REC 257
            .:|...|  ...:....:|||.|  |.|:|.|||||||.....:    |....||.|:|:  .:.
Human   478 KKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNN----RWYLAGVTSWGTGCGQR 538

  Fly   258 SGIGVYTDVYSYADWI 273
            :..||||.|.....||
Human   539 NKPGVYTKVTEVLPWI 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erasp	NP_725487.1	Tryp_SPc	40..276	CDD:238113	81/249 (33%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	6/19 (32%)
		Tryp_SPc	325..554	CDD:214473	79/248 (32%)