Protein Alignment Erasp and PRSS56

DIOPT Version :10

• Sequence 1: NP_725487.1
• Gene: Erasp / 246448
• FlyBaseID: FBgn0050090
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 83/283 - (29%)
• Similarity: 113/283 - (39%)
• Gaps: 76/283 - (26%)

  Fly    29 CG----LTANTIAF--KIIGGRDAIINSNPWMAYIHSSVKLICGGTLITQRFVLTAAHC------ 81
            ||    .|||....  :|:||..|...:.||:..:....:.:|||.|:...:|||||||
Human    88 CGERRPSTANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPN 152

  Fly    82 -------VNEGSAVKVRLGEYDDTATEDCNSKICIPRAEEHDVDMAFRHGKFSEIKNLNDIALLR 139
                   :.|||.     ||                :|||..|:....|.||......||:||::
Human   153 ELLWTVTLAEGSR-----GE----------------QAEEVPVNRILPHPKFDPRTFHNDLALVQ 196

  Fly   140 LAKFVTFKAHISPICI-------ILGTSKRELVDSIEWFVATGWG-------ETRTHRTRGVLQI 190
            |...|:......|:|:       ..||:          ....|||       |....|.
Human   197 LWTPVSPGGSARPVCLPQEPQEPPAGTA----------CAIAGWGALFEDGPEAEAVRE------ 245

  Fly   191 TQLQRYNSSQCMQALG-RLVQQNQICAGRL--GSDTCNGDSGGPLFQTVRHMDKMRPVQFGVVSY 252
            .::...::..|.:||| .|.....:|||.|  |.|:|.||||||| .......:.|.|.|||.|:
Human   246 ARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPL-TCSEPGPRPREVLFGVTSW 309

  Fly   253 GS--RECSGIGVYTDVYSYADWI 273
            |.  .|....||||.|..:.||:
Human   310 GDGCGEPGKPGVYTRVAVFKDWL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erasp	NP_725487.1	Tryp_SPc	40..276	CDD:238113	78/266 (29%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	78/266 (29%)
		PksD	<178..600	CDD:442550	52/172 (30%)