Protein Alignment Erasp and Cfd

DIOPT Version :10

• Sequence 1: NP_725487.1
• Gene: Erasp / 246448
• FlyBaseID: FBgn0050090
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 263
• Identity: 78/263 - (29%)
• Similarity: 122/263 - (46%)
• Gaps: 46/263 - (17%)

  Fly    39 KIIGGRDAIINSNPWMAYIHSSVKLICGGTLITQRFVLTAAHC---VNEGSAVKVRLGEYDDTAT 100
            :|:||::|:.::.|:||.:..:...:|||||:.:::||:||||   |.:...|:|.||.:..::.
  Rat    25 RILGGQEAMAHARPYMASVQVNGTHVCGGTLVDEQWVLSAAHCMDGVTKDEVVQVLLGAHSLSSP 89

  Fly   101 E------DCNSKICIPRAEEHDVDMAFRHGKFSEIKNLNDIALLRLAKFVTFKAHISPICIILGT 159
            |      |..|.:..|.:....|:              :|:.|.:|:...:...|:.|  :.|..
  Rat    90 EPYKHLYDVQSVVLHPGSRPDSVE--------------DDLMLFKLSHNASLGPHVRP--LPLQR 138

  Fly   160 SKRELVDSIEWFVATGWG-ETRTHRTRGVLQ---ITQLQRYNSSQCMQALGRLVQQNQICAGRLG 220
            ..||:.......|| ||| .|...|...|||   ::.:.| |:..........:.:|.:||....
  Rat   139 EDREVKPGTLCDVA-GWGVVTHAGRRPDVLQQLTVSIMDR-NTCNLRTYHDGAITKNMMCAESNR 201

  Fly   221 SDTCNGDSGGPLF--QTVRHMDKMRPVQFGVVSYGSRECSG---IGVYTDVYSYADWIATVVQQN 280
            .|||.|||||||.  ..|.          .||::|||.|..   .||:|.|.:|..||..|:..|
  Rat   202 RDTCRGDSGGPLVCGDAVE----------AVVTWGSRVCGNRRKPGVFTRVATYVPWIENVLSGN 256

  Fly   281 THV 283
            ..|
  Rat   257 VSV 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erasp	NP_725487.1	Tryp_SPc	40..276	CDD:238113	75/253 (30%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	75/253 (30%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)