Protein Alignment Erasp and Tmprss3

DIOPT Version :10

• Sequence 1: NP_725487.1
• Gene: Erasp / 246448
• FlyBaseID: FBgn0050090
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: XP_038954650.1
• Gene: Tmprss3 / 309665
• RGDID: 1310135
• Length: 454
• Species: Rattus norvegicus
• Alignment Length: 284
• Identity: 86/284 - (30%)
• Similarity: 132/284 - (46%)
• Gaps: 38/284 - (13%)

  Fly     8 ITALAIGVL----CSLGNGEYLE-PRCGLTANTIAFKIIGGRDAIINSNPWMAYIHSSVKLICGG 67
            :|||...|.    |:.|:...|: ..||:... .:.:|:||..:.:...||...:......:|||
  Rat   181 VTALHHSVYMREGCTSGHVVTLKCSACGMRTG-YSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGG 244

  Fly    68 TLITQRFVLTAAHCVNE-----GSAVKVRLGEYDDTATEDCNSKICIPRAEEHDVDMAFRHGKFS 127
            ::||..:::||||||.:     ...|:|.|....|:.         :|   .|.|:....|.|:.
  Rat   245 SVITPLWIVTAAHCVYDLYHPKSWTVQVGLVSLMDSP---------VP---SHLVEKIIYHSKYK 297

  Fly   128 EIKNLNDIALLRLAKFVTFKAHISPICIILGTSKRELVD-SIEWFVATGWGETR--THRTRGVLQ 189
            ..:..|||||::|::.:||...|.|||  |..|:....| .:.|  .:|||.|.  ......||.
  Rat   298 PKRLGNDIALMKLSEPLTFDETIQPIC--LPNSEENFPDGKLCW--TSGWGATEDGAGDASPVLN 358

  Fly   190 ITQLQRYNSSQC--MQALGRLVQQNQICAGRL--GSDTCNGDSGGPLFQTVRHMDKM-RPVQFGV 249
            ...:...::..|  ....|.::..:.:|||.|  |.|:|.|||||||....|.:.|: ....||:
  Rat   359 HAAVPLISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFGI 423

  Fly   250 VSYGSRECSGIGVYTDVYSYADWI 273
               |..|.:..||||.:.|:.|||
  Rat   424 ---GCAEVNKPGVYTRITSFLDWI 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Erasp	NP_725487.1	Tryp_SPc	40..276	CDD:238113	77/247 (31%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:464747	9/29 (31%)
		Tryp_SPc	216..444	CDD:214473	75/246 (30%)