Protein Alignment CG30088 and KLK4

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 70/258 - (27%)
• Similarity: 118/258 - (45%)
• Gaps: 23/258 - (8%)

  Fly    28 FLIPSCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAAHCMRPYLK 92
            :||.....|..|...::|:.|::....|.|:.|.|...:|:.|.|.::..:::|:||||.:....
Human    14 YLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYT 78

  Fly    93 VRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFDR-FLANDIALLKLSRNIRFNVHIQPIC 156
            :.||.|.:..:.:       |.::..:..|:.::..::| .||||:.|:||..::..:..|:.|.
Human    79 IGLGLHSLEADQE-------PGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSIS 136

  Fly   157 LILNPAAAPNVHEFQAFGWGQTETNHSANVLQTTVLTRYDNRHCRSVLSMPITINQLCV--GFQG 219
            :......|.|  .....|||.........|||...::......|..:.......:..|.  |...
Human   137 IASQCPTAGN--SCLVSGWGLLANGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQ 199

  Fly   220 SDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQS---PGVYTYVPNYIRWIRYVMQSN 279
            .|:|:|||||||:..       .||| |:||||...|..   |||||.:..:..||...:|::
Human   200 KDSCNGDSGGPLICN-------GYLQ-GLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	64/233 (27%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	65/235 (28%)