Protein Alignment CG30088 and PRSS2

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 89/264 - (33%)
• Similarity: 123/264 - (46%)
• Gaps: 54/264 - (20%)

  Fly    44 RIVRGKEAMLKSAPFMAYLYYSSEIH-CGGTIISSRYILTAAHCMRP--------------YLKV 93
            :||.|......|.|:...|  :|..| |||::||.:::::|.||.:.              .::|
Human    23 KIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQV 85

  Fly    94 RLGEHDITRNPDCQGGSCSPPAEEF----DIVLATKYKRFDRFLANDIALLKLSRNIRFNVHIQP 154
            |||||:|    :...|:     |:|    .|:...||.  .|.|.|||.|:|||.....|..:..
Human    86 RLGEHNI----EVLEGN-----EQFINAAKIIRHPKYN--SRTLDNDILLIKLSSPAVINSRVSA 139

  Fly   155 ICLILNPAAAPNVHEFQAFGWGQTETN-----HSANVLQTTVLTRYDNRHCRSVLSMPITINQLC 214
            |.|...|.||..  |....|||.|.::     .....|...||::.:   |.:.....||.|..|
Human   140 ISLPTAPPAAGT--ESLISGWGNTLSSGADYPDELQCLDAPVLSQAE---CEASYPGKITNNMFC 199

  Fly   215 VGF--QGSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQS--PGVYTYVPNYIRWIRYV 275
            |||  .|.|:|.||||||:|:...       || ||||:|....|.  |||||.|.||:.||:..
Human   200 VGFLEGGKDSCQGDSGGPVVSNGE-------LQ-GIVSWGYGCAQKNRPGVYTKVYNYVDWIKDT 256

  Fly   276 MQSN 279
            :.:|
Human   257 IAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	87/255 (34%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	88/257 (34%)