Protein Alignment CG30088 and PRSS1

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 84/249 - (33%)
• Similarity: 123/249 - (49%)
• Gaps: 38/249 - (15%)

  Fly    44 RIVRGKEAMLKSAPFMAYLYYSSEIH-CGGTIISSRYILTAAHCMRPYLKVRLGEHDITRNPDCQ 107
            :||.|......|.|:...|  :|..| |||::|:.:::::|.||.:..::||||||:|    :..
Human    23 KIVGGYNCEENSVPYQVSL--NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNI----EVL 81

  Fly   108 GGSCSPPAEEF-DIVLATKYKRFDR-FLANDIALLKLSRNIRFNVHIQPICLILNPAAAPNV-HE 169
            .|:     |:| :.....::.::|| .|.|||.|:|||.....|..:..|.|   |.|.|.. .:
Human    82 EGN-----EQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISL---PTAPPATGTK 138

  Fly   170 FQAFGWGQTETN-----HSANVLQTTVLTRYDNRHCRSVLSMPITINQLCVGF--QGSDTCSGDS 227
            ....|||.|.::     .....|...||::   ..|.:.....||.|..||||  .|.|:|.|||
Human   139 CLISGWGNTASSGADYPDELQCLDAPVLSQ---AKCEASYPGKITSNMFCVGFLEGGKDSCQGDS 200

  Fly   228 GGPLVTKVNYDGVWRYLQLGIVSFGDDKCQ--SPGVYTYVPNYIRWIRYVMQSN 279
            |||:|......||        ||:||...|  .|||||.|.||::||:..:.:|
Human   201 GGPVVCNGQLQGV--------VSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAAN 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	82/240 (34%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	81/240 (34%)