Protein Alignment CG30088 and KLK12

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 92/274 - (33%)
• Similarity: 123/274 - (44%)
• Gaps: 56/274 - (20%)

  Fly     9 SIYICMCVCLVLQEQVAANFLIPSCGVSYESNVAT-RIVRGKEAMLKSAPFMAYLYYSSEIHCGG 72
            ||::.:||                .|:   |..|| :|..|.|....|.|:...|:..:.:.|||
Human     4 SIFLLLCV----------------LGL---SQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGG 49

  Fly    73 TIISSRYILTAAHCMRPYLKVRLGEH-----DITRNPDCQGGSCSPPAEEFDIVLATKYKRFDRF 132
            .:|..|::||||||......||||||     |.|......|.|.:.|..   :..:|.::
Human    50 VLIDHRWVLTAAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY---LGASTSHE----- 106

  Fly   133 LANDIALLKLSRNIRFNVHIQPICLILNPAAAPNVHEFQAFGWGQTETNHSAN----VLQTTVLT 193
              :|:.||:|...:|....:||:.|..:.|.|..  |....|||  .|||..|    :||...|:
Human   107 --HDLRLLRLRLPVRVTSSVQPLPLPNDCATAGT--ECHVSGWG--ITNHPRNPFPDLLQCLNLS 165

  Fly   194 RYDNRHCRSVLSMPITINQLCV-GFQGSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGD-DKC 256
            ...:..|..|....||.|.:|. |..|.|.|.||||||||.    .||   || |:||:|. ..|
Human   166 IVSHATCHGVYPGRITSNMVCAGGVPGQDACQGDSGGPLVC----GGV---LQ-GLVSWGSVGPC 222

  Fly   257 QS---PGVYTYVPN 267
            ..   ||||||:.|
Human   223 GQDGIPGVYTYICN 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	84/237 (35%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	83/235 (35%)