DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30088 and ea

DIOPT Version :9

Sequence 1:	NP_725488.3	Gene:	CG30088 / 246447	FlyBaseID:	FBgn0050088	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	300	Identity:	97/300 - (32%)
Similarity:	149/300 - (49%)	Gaps:	60/300 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VAANFLIP---SCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSE-----IHCGGTIISSRYI 80
            |.:|.|:|   .||    :.::.||..|.:..:...|:||.:.|:..     .||||::||:||:
  Fly   108 VTSNSLLPLPGQCG----NILSNRIYGGMKTKIDEFPWMALIEYTKSQGKKGHHCGGSLISTRYV 168

  Fly    81 LTAAHCMR--------PYLKVRLGEHDITRNPDCQGG-----SCSPPAEEF---------DIVLA 123
            :||:||:.        ....|||||.|...||||:..     .|:||..:.         |.:.|
  Fly   169 ITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPDYIPA 233

  Fly   124 TKYKRFDRFLANDIALLKLSRNIRFNVHIQPICLILN---PAAAPNVHEFQAFGWGQTETNHSAN 185
            :|.:      .||||||:|::.:.:...::||||.|:   .:|..:.......|||:||...::|
  Fly   234 SKNQ------VNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKTEQLSASN 292

  Fly   186 VLQTTVLTRYDNRHCRSVLS---MPITINQLCV-GFQGSDTCSGDSGGPLV----TKVN-YDGVW 241
            :.....:..:....|::|.|   :.:...|:|. |.:|.|:|.|||||||:    .||| |
  Fly   293 LKLKAAVEGFRMDECQNVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPLIGLDTNKVNTY---- 353

  Fly   242 RYLQLGIVSFGDDKCQS---PGVYTYVPNYIRWIRYVMQS 278
             |...|:||||...|..   |||||.|..|:.||:..::|
  Fly   354 -YFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWIQNTIES 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	44..272	CDD:214473	88/269 (33%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	88/269 (33%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	88/269 (33%)
		Tryp_SPc	128..389	CDD:238113	89/271 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010