DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30088 and CG33465

DIOPT Version :9

Sequence 1:	NP_725488.3	Gene:	CG30088 / 246447	FlyBaseID:	FBgn0050088	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	83/277 - (29%)
Similarity:	130/277 - (46%)	Gaps:	27/277 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 ISLASTSIYICMCVCLVLQEQVAANFLIPSCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSE 67
            :|||...:.:|         |..|..|...|   ::...:..| .......::||:||.:|.:::
  Fly     5 LSLALIGLVLC---------QGLAQLLDKKC---HDPKTSENI-NFNHGATETAPWMASIYKNNQ 56

  Fly    68 IHCGGTIISSRYILTAAHCMR--PYLKVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRF- 129
            ..|.||::...::||||.|:.  ..|.|..|.::..|:     .|.....|::.:.:|.::..|
  Fly    57 FICDGTLVHKLFVLTAASCISKDSQLYVLFGMYNQYRD-----ASQFFNNEQYGVAVALQHSNFR 116

  Fly   130 DRFLANDIALLKLSRNIRFNVHIQPICLILNPA--AAPNVHEFQAFGWGQTETNHSANVLQTTVL 192
            .....|||.||:|...:....||:|||:||:..  :|| ...|:.|||.|..|..|:.|.||..|
  Fly   117 PNNGVNDIGLLRLYGEVTHYAHIRPICIILDHVVKSAP-FERFEGFGWQQQGTEASSQVRQTVYL 180

  Fly   193 TRYDNRHC-RSVLSMPITINQLCVGFQGSDTCSGDSGGPLVTKVNYDGVWRY-LQLGIVSFGDDK 255
            ::.....| |:...:||...|.|.|.:....|..:||.||.....| ||... :|:|:||:|.:.
  Fly   181 SQKKPFECHRNGQLLPINEGQFCAGNRDRSFCRSNSGSPLTADFTY-GVKNITVQVGLVSYGSEL 244

  Fly   256 CQSPGVYTYVPNYIRWI 272
            |....|||.|..:..||
  Fly   245 CSPTSVYTDVVAFKDWI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	44..272	CDD:214473	73/234 (31%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	75/235 (32%)
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	73/223 (33%)
		Tryp_SPc	46..261	CDD:214473	71/221 (32%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463397
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.790