Protein Alignment CG30088 and KLK1

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 85/288 - (29%)
• Similarity: 127/288 - (44%)
• Gaps: 48/288 - (16%)

  Fly    11 YICMCVCLVLQEQVAANFLIPSCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTII 75
            ::.:|:.|.|.            |......:.:|||.|.|....|.|:.|.||:.|...|||.::
Human     3 FLVLCLALSLG------------GTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILV 55

  Fly    76 SSRYILTAAHCMRPYLKVRLGEHDITRNPDCQ---GGSCSPPAEEFDIVLATKYKR-FDRFLAND 136
            ..:::||||||:....::.||.|::..:.:..   ..|.|.|...|::.|...:.| .|...::|
Human    56 HRQWVLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120

  Fly   137 IALLKLSRNIRFNVHIQPICLILN-------PAAAPNV-HEFQAFGWGQTETNHSA--NVLQTTV 191
            :.||:|:         :|...|.:       |...|.| ....|.|||..|..:.:  :.||...
Human   121 LMLLRLT---------EPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVD 176

  Fly   192 LTRYDNRHCRSVLSMPITINQLCVGF--QGSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDD 254
            |....|..|:......:|...||||.  .|.|||.|||||||:.    |||   || |:.|:|..
Human   177 LKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMC----DGV---LQ-GVTSWGYV 233

  Fly   255 KC---QSPGVYTYVPNYIRWIRYVMQSN 279
            .|   ..|.|...|.:|::||...:..|
Human   234 PCGTPNKPSVAVRVLSYVKWIEDTIAEN 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	78/246 (32%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	79/248 (32%)