Protein Alignment CG30088 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 80/274 - (29%)
• Similarity: 119/274 - (43%)
• Gaps: 50/274 - (18%)

  Fly    30 IPSCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAAHC-------- 86
            :..||........||:|.|..|.....|:...|...|...||.|::..|::|:||||
Human   523 LQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQ 587

  Fly    87 MRPYL-----------KVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFDRFLANDIALL 140
            :|.:|           .|::|...:..:|....|                      .|..|:|:|
Human   588 VRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPG----------------------ILDFDLAVL 630

  Fly   141 KLSRNIRFNVHIQPICLILNPAAAPNVHEFQAFGWGQTETNHSA--NVLQTTVLTRYDNRHCRSV 203
            :|:..:.||.:|||:||.|.....|...:....|||.|:..::.  .:||...:...|.:.|..:
Human   631 ELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVL 695

  Fly   204 LSMPITINQLCVGF-QGS-DTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQ--SPGVYTY 264
            .:..:|...:|.|| :|. |:|.|||||||..: ...||: || .||||:|....|  .|||||.
Human   696 YNFSLTDRMICAGFLEGKVDSCQGDSGGPLACE-EAPGVF-YL-AGIVSWGIGCAQVKKPGVYTR 757

  Fly   265 VPNYIRWIRYVMQS 278
            :.....||..:|.|
Human   758 ITRLKGWILEIMSS 771

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	73/252 (29%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473
		Tryp_SPc	538..768	CDD:238113	74/254 (29%)
		Pneumo_att_G	<717..>867	CDD:114270	27/58 (47%)
		Tryp_SPc	861..1087	CDD:238113