Protein Alignment CG30088 and KLK3

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 82/257 - (31%)
• Similarity: 119/257 - (46%)
• Gaps: 35/257 - (13%)

  Fly    41 VATRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAAHCMRPYLKVRLGEHDITRNPD 105
            :.:|||.|.|....|.|:...:.......|||.::..:::||||||:|....:.||.|.:. :|:
Human    21 ILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF-HPE 84

  Fly   106 CQGG----SCSPPAEEFDIVLATKYKRFDRFL------ANDIALLKLSRNIRFNVHIQPICL-IL 159
            ..|.    |.|.|...:|:.|..     :|||      ::|:.||:||........::.:.| ..
Human    85 DTGQVFQVSHSFPHPLYDMSLLK-----NRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 144

  Fly   160 NPAAAPNVHEFQAFGWGQTETNH--SANVLQTTVLTRYDNRHCRSVLSMPITINQLCVG--FQGS 220
            .||.....:   |.|||..|...  :...||...|....|..|..|....:|...||.|  ..|.
Human   145 EPALGTTCY---ASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGK 206

  Fly   221 DTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKC---QSPGVYTYVPNYIRWIRYVMQSN 279
            .|||||||||||.    :||   || ||.|:|.:.|   :.|.:||.|.:|.:||:..:.:|
Human   207 STCSGDSGGPLVC----NGV---LQ-GITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	79/245 (32%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	80/247 (32%)