Protein Alignment CG30088 and GZMM

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_005308.2
• Gene: GZMM / 3004
• HGNCID: 4712
• Length: 257
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 80/275 - (29%)
• Similarity: 126/275 - (45%)
• Gaps: 45/275 - (16%)

  Fly    22 EQVAANFLIPSCG-VSYESNVATRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAAH 85
            |...::.|:.:.| :|..|:..|:|:.|:|.:..|.|:||.|..:....|||.::..:::|||||
Human     2 EACVSSLLVLALGALSVGSSFGTQIIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAH 66

  Fly    86 CM---RPYLKVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFDRF--LANDIALLKLSRN 145
            |:   ...|::.||.|.:           ..|...|.|..|.::.|:...  |.||:|||:|...
Human    67 CLAQRMAQLRLVLGLHTL-----------DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGK 120

  Fly   146 IRFNVHIQPICLILNPAAAPNVHEFQA-------FGWGQT-ETNHSANVLQTTVLTRYDNRHCRS 202
            ::.:..|:|:.|       |:..:..|       .|||.| :....:.||:...|...|.|.|.:
Human   121 VKPSRTIRPLAL-------PSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNN 178

  Fly   203 --VLSMPITINQLCVGFQGSD--TCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQ---SPG 260
              ..:..::.:.:|:.....|  .|.||||||||.     |..|.| ..::||....|.   .|.
Human   179 SRFWNGSLSPSMVCLAADSKDQAPCKGDSGGPLVC-----GKGRVL-ARVLSFSSRVCTDIFKPP 237

  Fly   261 VYTYVPNYIRWIRYV 275
            |.|.|..|:.|||.|
Human   238 VATAVAPYVSWIRKV 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	71/247 (29%)
GZMM	NP_005308.2	Tryp_SPc	26..252	CDD:238113	73/249 (29%)