DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30088 and CG30187

DIOPT Version :9

Sequence 1:	NP_725488.3	Gene:	CG30088 / 246447	FlyBaseID:	FBgn0050088	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001246475.2	Gene:	CG30187 / 246509	FlyBaseID:	FBgn0050187	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	96/266 - (36%)
Similarity:	145/266 - (54%)	Gaps:	23/266 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LQEQVAANFLIPSCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAA 84
            |::..|:.||...||:    |:|.:|..|..|..:::.:||.::..:...||||:|..|::||||
  Fly    15 LKDVGASIFLDQICGI----NIALKITGGHNAAFQNSVWMAAVHNRTHFICGGTLIHKRFVLTAA 75

  Fly    85 HCM--RPYLKVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFD--RFLANDIALLKLSRN 145
            ||:  :....|.||.:           :.|.||:..|::.|..:..||  ....|||.|||||.:
  Fly    76 HCIVDQDVQSVSLGAY-----------NKSDPADRKDVITAVVHSSFDVRASYENDIGLLKLSSD 129

  Fly   146 IRFNVHIQPICLILNPAAA---PNVHEFQAFGWGQTETNHSANVLQTTVLTRYDNRHCRSVLSMP 207
            :.||..|:|||::||.:.|   .|:..|:|||||....|.::::|||.:|...|...|...||:.
  Fly   130 VIFNALIRPICIVLNKSMANHMRNMRTFKAFGWGTLRGNKTSDILQTIILNHLDREECYMELSVY 194

  Fly   208 ITINQLCVGFQGSDTCSGDSGGPLVTKVNYDGVW-RYLQLGIVSFGDDKCQSPGVYTYVPNYIRW 271
            .:..|:|.|....|||.|||||||...|...|:. |.:|.||:|.|...|...||||.:.::..|
  Fly   195 PSEKQICAGVPSGDTCGGDSGGPLTNDVFIQGIGNREVQFGIISVGKTSCDGQGVYTDLMSFADW 259

  Fly   272 IRYVMQ 277
            |:..::
  Fly   260 IKMTIE 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	44..272	CDD:214473	86/235 (37%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	87/235 (37%)
CG30187	NP_001246475.2	Tryp_SPc	35..260	CDD:214473	86/235 (37%)
CG30187	NP_001246475.2	Trypsin	316..>384	CDD:355628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	108	1.000	Inparanoid score	I3480
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860