DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30088 and CG30091

DIOPT Version :9

Sequence 1:	NP_725488.3	Gene:	CG30088 / 246447	FlyBaseID:	FBgn0050088	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	88/266 - (33%)
Similarity:	134/266 - (50%)	Gaps:	21/266 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 AANFLIPSCGVSYESNVATRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAAHCM-- 87
            :|..|...|||..:  :..:||.|.:|.....|:||.:..:.|..|||::|:::::|||||||
  Fly    19 SARLLDEDCGVPMQ--LIPKIVGGVDAGELKNPWMALIKTNDEFICGGSVITNKFVLTAAHCMCT 81

  Fly    88 -------RPYLKVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFD-RFLANDIALLKLSR 144
                   ...|.|.||.:.:...     |..:.|.|.:::.....:..|. :...||||||:|.:
  Fly    82 DEECIVKYTQLTVTLGVYHLLAT-----GEHNHPHEIYNVERVYIHDSFAIQNYRNDIALLRLQK 141

  Fly   145 NIRFNVHIQPICLILNPAAAPN---VHEFQAFGWGQTETNHSANVLQTTVLTRYDNRHCRSVLSM 206
            :|.:...|:|:|::||....|.   :.||.|.|||.|.....:|.||...:.|.|.:.|.:....
  Fly   142 SIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMVKIYRIDRKMCEAAFWY 206

  Fly   207 PITINQLCVGFQ-GSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQSPGVYTYVPNYIR 270
            .......|.|.. |.|||..||||||...:.:||:.|..||||||.|.:.|:..|:||.|..:|.
  Fly   207 TFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTEDCRGFGMYTDVMGHID 271

  Fly   271 WIRYVM 276
            :|..::
  Fly   272 FIERIV 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	44..272	CDD:214473	82/241 (34%)
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	82/241 (34%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	82/241 (34%)
		Tryp_SPc	37..276	CDD:238113	83/243 (34%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463348
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.640