Protein Alignment CG30088 and F11

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: XP_005262878.1
• Gene: F11 / 2160
• HGNCID: 3529
• Length: 626
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 82/270 - (30%)
• Similarity: 124/270 - (45%)
• Gaps: 41/270 - (15%)

  Fly    26 ANFLIPSCGVSYE--SNVATRIVRGKEAMLKSAPFMAYLYYSSEIH---CGGTIISSRYILTAAH 85
            :.:.:..|.:..|  :.:..|||.|..::....|:...|:.:|...   |||:||.:::||||||
Human   368 SGYTLRLCKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAH 432

  Fly    86 C---------MRPYLKVRLGEHDITRNPDCQGGSCSPPAEEFDIVLATKYKRFDRFLANDIALLK 141
            |         :|.|..: |.:.:|..:....|..        :|::..:||..:.  ..||||||
Human   433 CFYGVESPKILRVYSGI-LNQSEIKEDTSFFGVQ--------EIIIHDQYKMAES--GYDIALLK 486

  Fly   142 LSRNIRFNVHIQPICLILNPAAAP-NV--HEFQAFGWGQTETNHS-ANVLQTTVLTRYDNRHC-R 201
            |...:.:....:||||   |:... ||  .:....|||..:.... .|.||...:....|..| :
Human   487 LETTVNYTDSQRPICL---PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK 548

  Fly   202 SVLSMPITINQLCVGFQ--GSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQ--SPGVY 262
            ......||...:|.|::  |.|.|.|||||||..|  ::.||..  :||.|:|:...|  .||||
Human   549 RYRGHKITHKMICAGYREGGKDACKGDSGGPLSCK--HNEVWHL--VGITSWGEGCAQRERPGVY 609

  Fly   263 TYVPNYIRWI 272
            |.|..|:.||
Human   610 TNVVEYVDWI 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	79/249 (32%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	0/6 (0%)
		Tryp_SPc	389..619	CDD:238113	77/247 (31%)