Protein Alignment CG30088 and F10

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 84/253 - (33%)
• Similarity: 125/253 - (49%)
• Gaps: 24/253 - (9%)

  Fly    40 NVATRIVRGKEAMLKSAPFMAYLY-YSSEIHCGGTIISSRYILTAAHCM--RPYLKVRLGEHDIT 101
            |..||||.|:|......|:.|.|. ..:|..|||||:|..||||||||:  ....|||:|:.:..
Human   230 NNLTRIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 294

  Fly   102 RNPDCQGGSCSPPAEEFDIVLATKYKRFDRFLAN-DIALLKLSRNIRFNVHIQPICLILNPAAAP 165
            :.   :||..   ..|.::|:  |:.||.:...: |||:|:|...|.|.:::.|.||.....|..
Human   295 QE---EGGEA---VHEVEVVI--KHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAES 351

  Fly   166 NVHEFQ---AFGWGQT-ETNHSANVLQTTVLTRYDNRHCRSVLSMPITINQLCVGF--QGSDTCS 224
            .:...:   ..|:|:| |....:..|:...:...|...|:...|..||.|..|.|:  :..|.|.
Human   352 TLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQ 416

  Fly   225 GDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQSP--GVYTYVPNYIRWIRYVMQSNG 280
            ||||||.||:...    .|...||||:|:...:..  |:||.|..:::||...|::.|
Human   417 GDSGGPHVTRFKD----TYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRG 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	78/239 (33%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	79/240 (33%)
		O-glycosylated at one site	476..485