Protein Alignment CG30088 and Ctsg

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_031826.1
• Gene: Ctsg / 13035
• MGIID: 88563
• Length: 261
• Species: Mus musculus
• Alignment Length: 249
• Identity: 71/249 - (28%)
• Similarity: 119/249 - (47%)
• Gaps: 28/249 - (11%)

  Fly    38 ESNVATRIVRGKEAMLKSAPFMAYLYYSSE---IHCGGTIISSRYILTAAHCMRPYLKVRLGEHD 99
            :.:.|.:|:.|:||...|.|:||:|...|.   ..|||.::...::||||||:...:.|.||.|:
Mouse    14 QGDEAGKIIGGREARPHSYPYMAFLLIQSPEGLSACGGFLVREDFVLTAAHCLGSSINVTLGAHN 78

  Fly   100 ITRNPDCQGGSCSPPAEEFDIVLATKYKRFD-RFLANDIALLKLSRNIRFNVHIQPICLILNPAA 163
            |......|        :...::.|.::..:: :.:.|||.||:|.|..|.:..::|:.|   |.|
Mouse    79 IQMRERTQ--------QLITVLRAIRHPDYNPQNIRNDIMLLQLRRRARRSGSVKPVAL---PQA 132

  Fly   164 APNVHE---FQAFGWGQTETNHSANVLQTTVLTRYDNRHCRSVLSMPITINQLCVG--FQGSDTC 223
            :..:..   ....|||:...:...||||...|....::.|.:......:..|:|||  .:.....
Mouse   133 SKKLQPGDLCTVAGWGRVSQSRGTNVLQEVQLRVQMDQMCANRFQFYNSQTQICVGNPRERKSAF 197

  Fly   224 SGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDKCQSPGVYTYVPNYIRWIRYVMQ 277
            .||||||||..        .:..||||:|.:....|.|:|.:.:::.||:..|:
Mouse   198 RGDSGGPLVCS--------NVAQGIVSYGSNNGNPPAVFTKIQSFMPWIKRTMR 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	68/236 (29%)
Ctsg	NP_031826.1	Tryp_SPc	21..241	CDD:238113	69/238 (29%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	21..25		1/3 (33%)
		Important for antimicrobial activity. /evidence=ECO:0000250|UniProtKB:P08311	97..111		3/13 (23%)