Protein Alignment CG30088 and KLK11

DIOPT Version :10

• Sequence 1: NP_725488.3
• Gene: CG30088 / 246447
• FlyBaseID: FBgn0050088
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: XP_011524671.1
• Gene: KLK11 / 11012
• HGNCID: 6359
• Length: 307
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 82/287 - (28%)
• Similarity: 128/287 - (44%)
• Gaps: 81/287 - (28%)

  Fly    43 TRIVRGKEAMLKSAPFMAYLYYSSEIHCGGTIISSRYILTAAHCMRPYLK--------------- 92
            |||::|.|....|.|:.|.|:..:.:.||.|:|:.|::||||||::|::.
Human    52 TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPWVSLTSPTHVSPDLSSSN 116

  Fly    93 ----------VRLGEHDITRNPDCQ---GGSCSPPAEEFDIVLATKYKRFDRFLANDIALLKLSR 144
                      |.||:|::.:...|:   ..:.|.|...|:..|..|..|      |||.|:|::.
Human   117 YCLSHLSRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHR------NDIMLVKMAS 175

  Fly   145 NIRFNVHIQPI------------CLILNPAAAPNVHEFQAFGWGQTET-----NHSANVLQTTVL 192
            .:.....::|:            |||              .|||.|.:     .|:......|::
Human   176 PVSITWAVRPLTLSSRCVTAGTSCLI--------------SGWGSTSSPQLRLPHTLRCANITII 226

  Fly   193 TRYDNRHCRSVLSMPITINQLCVGFQ--GSDTCSGDSGGPLVTKVNYDGVWRYLQLGIVSFGDDK 255
               :::.|.:.....||...:|...|  |.|:|.||||||||..       :.|| ||:|:|.|.
Human   227 ---EHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCN-------QSLQ-GIISWGQDP 280

  Fly   256 C---QSPGVYTYVPNYIRWIRYVMQSN 279
            |   :.|||||.|..|:.||:..|::|
Human   281 CAITRKPGVYTKVCKYVDWIQETMKNN 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30088	NP_725488.3	Tryp_SPc	45..273	CDD:238113	77/277 (28%)
KLK11	XP_011524671.1	Tryp_SPc	53..300	CDD:214473	77/277 (28%)