Protein Alignment CG30087 and KLK6

DIOPT Version :10

• Sequence 1: NP_725489.2
• Gene: CG30087 / 246446
• FlyBaseID: FBgn0050087
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 81/239 - (33%)
• Similarity: 127/239 - (53%)
• Gaps: 23/239 - (9%)

  Fly    41 RVVNGKEAVIRSAPFMVYVTNNSLTHCGGSILNSRYILTAAHCVFPNLRLRLGEHNIRTDPDCQG 105
            ::|:|......|.|:...:..:....|||.:::..::||||||..|||::.||:||:|.....|
Human    21 KLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQRESSQ- 84

  Fly   106 SNCSPRSEEYGIMKAITHRFYNAANHVNDIALLKLNRSINFNVHIQPICILLNPASAPSVATYQT 170
                   |:..:::|:.|..|:||:|..||.||:|.|....:..|||: .|....||.:.:.: .
Human    85 -------EQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPL-PLERDCSANTTSCH-I 140

  Fly   171 FGWGETKKNGFPHLLQTAELRAYDAAYCSRSFHAYMNGNQICAGHEE--RDTCAGDSGGPLVTRV 233
            .|||:|....||..:|.|.:.......|..::...:..|.:|||.|:  :|:|.||||||||..
Human   141 LGWGKTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCG- 204

  Fly   234 DFDGVKRYLQLGIVSYGPTDC---QSPGVYTYVPNYINWIRRAM 274
              |.::     |:||:|...|   :.|||||.|..|.|||::.:
Human   205 --DHLR-----GLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30087	NP_725489.2	Tryp_SPc	42..272	CDD:238113	81/234 (35%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	79/231 (34%)