Protein Alignment CG30087 and PRSS2

DIOPT Version :10

• Sequence 1: NP_725489.2
• Gene: CG30087 / 246446
• FlyBaseID: FBgn0050087
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 76/257 - (29%)
• Similarity: 120/257 - (46%)
• Gaps: 39/257 - (15%)

  Fly    41 RVVNGKEAVIRSAPFMVYVTNNSLTHCGGSILNSRYILTAAHCV--------------FPNLRLR 91
            ::|.|......|.|:.|.: |:....||||:::.:::::|.||.              :..:::|
Human    23 KIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVR 86

  Fly    92 LGEHNIRTDPDCQGSNCSPRSEEY-GIMKAITHRFYNAANHVNDIALLKLNRSINFNVHIQPICI 155
            ||||||..   .:|      :|:: ...|.|.|..||:....|||.|:||:.....|..:..|.:
Human    87 LGEHNIEV---LEG------NEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISL 142

  Fly   156 LLNPASAPSVATYQTF-GWGETKKNG--FPHLLQTAELRAYDAAYCSRSFHAYMNGNQICAGHEE 217
               |.:.|:..|.... |||.|..:|  :|..||..:......|.|..|:...:..|..|.|..|
Human   143 ---PTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLE 204

  Fly   218 --RDTCAGDSGGPLVTRVDFDGVKRYLQLGIVSYGPTDCQSPGVYTYVPNYINWIRRAMLIN 277
              :|:|.||||||:|:..:..|:..:      .||......|||||.|.||::||:..:..|
Human   205 GGKDSCQGDSGGPVVSNGELQGIVSW------GYGCAQKNRPGVYTKVYNYVDWIKDTIAAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30087	NP_725489.2	Tryp_SPc	42..272	CDD:238113	75/249 (30%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	75/250 (30%)