DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG30087 and PLAT

DIOPT Version :10

Sequence 1:	NP_725489.2	Gene:	CG30087 / 246446	FlyBaseID:	FBgn0050087	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_000921.1	Gene:	PLAT / 5327	HGNCID:	9051	Length:	562	Species:	Homo sapiens

Alignment Length:	41	Identity:	8/41 - (19%)
Similarity:	19/41 - (46%)	Gaps:	11/41 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 IDLLVARGSVSQTL------LSPRM-----LFHTVADILDR 214
            :|.::.:..|:...      :||::     :.|.|..:||:
Human    65 VDSMLDKSEVNNPAIGKDENISPQVKGDEDMGHEVGSMLDK 105

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30087	NP_725489.2	Tryp_SPc	42..272	CDD:238113	8/41 (20%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494	2/17 (12%)
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967	6/20 (30%)
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005
		Tryp_SPc	313..559	CDD:238113
Blue background indicates that the domain is not in the aligned region.

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