Protein Alignment CG30087 and KLK8

DIOPT Version :10

• Sequence 1: NP_725489.2
• Gene: CG30087 / 246446
• FlyBaseID: FBgn0050087
• Length: 277
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 78/259 - (30%)
• Similarity: 125/259 - (48%)
• Gaps: 34/259 - (13%)

  Fly    27 NPLCGVTYESQTAM-RVVNGKEAVIRSAPFMVYVTNNSLTHCGGSILNSRYILTAAHCVFPNLRL 90
            |||......|:... :|:.|.|....|.|:...:.......|||.::...::||||||..|...:
Human    62 NPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTV 126

  Fly    91 RLGEHNIRTDPDCQGSNCSPRSEEYGIMKAITHRFYNAA---NHVNDIALLKLNRSINFNVHIQP 152
            |||:|:::        |.....:|..::::|.|..||::   :|.:|:.||:|....:....::|
Human   127 RLGDHSLQ--------NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKP 183

  Fly   153 ICI---LLNPASAPSVATYQTFGWG--ETKKNGFPHLLQTAELRAYDAAYCSRSFHAYMNGNQIC 212
            |.:   ...|....:|:     |||  .:.:..||..|..||::.:....|..::...:....:|
Human   184 ISLADHCTQPGQKCTVS-----GWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVC 243

  Fly   213 AGHEE-RDTCAGDSGGPLVTRVDFDGVKRYLQLGIVSYGPTDC---QSPGVYTYVPNYINWIRR 272
            ||..: .|||.||||||||.    ||.   || ||.|:|...|   ..|||||.:..|::||::
Human   244 AGSSKGADTCQGDSGGPLVC----DGA---LQ-GITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30087	NP_725489.2	Tryp_SPc	42..272	CDD:238113	74/241 (31%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	72/240 (30%)