Protein Alignment Rif1 and rif1

DIOPT Version :9

• Sequence 1: NP_725497.1
• Gene: Rif1 / 246445
• FlyBaseID: FBgn0050085
• Length: 1416
• Species: Drosophila melanogaster
• Sequence 2: NP_593910.2
• Gene: rif1 / 2542144
• PomBaseID: SPAC6F6.17
• Length: 1400
• Species: Schizosaccharomyces pombe
• Alignment Length: 1402
• Identity: 272/1402 - (19%)
• Similarity: 456/1402 - (32%)
• Gaps: 517/1402 - (36%)

  Fly    62 WLGDILPLMFDADRKIQDCAVAALAEALVALDVSVIHSAKCWPQIRSEFVDKY---TIIIGEMRD 123
            |...:|..:.||.|.|::.|:      |:|||:|           :..:.||.   ||:.....|
pombe   277 WAPYLLACLVDASRPIREKAL------LLALDLS-----------KHLYHDKLVARTILANFRSD 324

  Fly   124 AKNS--------NWHKI-------------WTLLVQIMDEDLLRGCVYINKFLALVELGFRNPDN 167
            .|.:        .:.|:             |..::.::....:....|.|.:|.:::|.|.:.:.
pombe   325 IKGTAFVLIMTEQFEKLVIEEDDGVYVAHAWAAIISVLGGARISSWEYFNTWLKIIQLCFNSMNP 389

  Fly   168 GVRSEAFLCWRVLIKIFAAYDELTSA-KRLRLLLIPLRTSQSRSSHVSGIKLRVWWYLL----SC 227
            ..:..|...|..||..|:..:.||.| |||.||..|: :....|.::..:|......|:    :|
pombe   390 LTKCAAQTSWIRLIHEFSLSETLTQATKRLTLLCQPI-SMVLGSRNLPTVKNAAMTTLIALIYAC 453

  Fly   228 L-----DHELPKSFDSAVEHFL--------------AFMLGGGPRNLATG-------LAHNYQTA 266
            |     |..|...:||.:.:.|              :.:|......|:.|       :......|
pombe   454 LRPGISDAMLSLLWDSVIVNILEKCALKNEVTIFESSNILLALFNTLSNGVWKDDRLVCRESVEA 518

  Fly   267 RELALPCLVALWGVESS-----EPLQRLMRELRLE-TLVQPSPL-----------MSVEVFQQHW 314
            :|  ||.|..:| |.::     ||::.|:...:.: |:...:|.           .|..|:..:.
pombe   519 KE--LPKLNPVW-VRANCSRTIEPVKTLLLLAKPDHTVKTTTPARKQHIRGLSYEQSSSVWSTYI 580

  Fly   315 KPLLAAAVSGLKLLTENDATEAEQLLLQLLVRNLCLAMFRLAVAPFNVACCSEIEKILQAEDNSG 379
            |.|.:|....:|...|..             |.:|             ..||.:.|.|.::
pombe   581 KCLASAGQKEIKRSVETG-------------RAIC-------------CICSSLHKFLYSK---- 615

  Fly   380 GRVVRALFNTIAADNLVMERVSGSDHL--DVLEA----------YL----KLVLKSKTEV----- 423
                     :|..|.|.:||||....:  ..:||          ||    :|||..:|:.
pombe   616 ---------SIRKDELYVERVSRFALMVKSAIEAFGINTFVEASYLVSDNQLVLIDQTKAIDSYD 671

  Fly   424 -----PAAILQRSIACIFAVDRIEANNQNEFRML-GSFAELLMQANDEEDFEGFAFKLQ-VWRQV 481
                 |...|..|:|.:        .|...|..: .:::.:|  ::.||....|..||. :|..|
pombe   672 HVPISPLIYLLHSLALL--------TNGTLFSTVHAAYSSIL--SSIEEYHLRFGLKLMLLWDCV 726

  Fly   482 SQ-------ALSNYLRNNALEYRVAHNASLLDTWLLWPLQTLAAFAGRRASNSFDASFCDQWRQL 539
            |.       .|:..|        |:|..|.|.:..|     |:....|..:||.:..|.::.|.:
pombe   727 SPLSDDGTLVLARVL--------VSHEVSRLTSEAL-----LSELKSRNGNNSVEEGFSEEERSI 778

  Fly   540 VNAGQNAPGRKKFLTDLKATLTDLLKSKDEPLFAELFDAYVTSLIKFGLCKEA-PLYKDVFGLLQ 603
                         |..|.:.........|......|...|.|::.||..|... |...|.|   .
pombe   779 -------------LLKLLSWNVKFCSISDAGSVNNLLQQYFTAIYKFEGCGSVFPFVVDPF---T 827

  Fly   604 TIFEQPSS---------------QKTLEACLNTLR--NLVVELRQ-----NELMVVFDSLKPTLS 646
            ||.:...|               ..|.|:|...|.  .|...:||     |.::.::::|...||
pombe   828 TILDDVLSFEANKVYSFAISLMKVSTFESCTKELPPVTLPENIRQHLDSYNHMVELYNTLLQRLS 892

  Fly   647 SGIQCWNKMKCEGGFLEEWKRGIQEKFRKLPMKTMANQLKELFKADDLFVIIPSVWSLNP----E 707
            |..|.  .::|.  :|.|    :.|..:|:|.:.:.:.:.:|.|.     :|| .:.:|.    |
pombe   893 SSDQV--DLQCR--YLHE----LSEFIKKIPKEFIFHTICKLSKG-----LIP-CFLMNAFPQLE 943

  Fly   708 KLTDRQK--------------ERFAEKSDI-----PAL---YNDMSQSQDSASIKPWTPKKVVIA 750
            |.|..||              ...|..|:|     |.|   ...:|:....|:||.|.
pombe   944 KSTTLQKSCTNFCILILQLLLNSTATASNILESLSPLLTSGLKSISKEVVLAAIKFWN------- 1001

  Fly   751 KSKQGELALTGKDDNGEVIDITASEESEKEPVRVDVVTPIRKKPGRKSQAQKELEAAARA----- 810
                               .:....|||:.|:                :.||.:...::.
pombe  1002 -------------------QVFGKFESEEYPI----------------ELQKTISYLSKTYIILL 1031

  Fly   811 --ASLAEEPPKRQTRTRAAQKETEQVAQPQPAFEPQLRSPKKLPPSPVVQSTAAAVKQAKVAKPT 873
              .||.  |..:|...::::|.::.:....     :|||..|..|
pombe  1032 PFQSLC--PGGKQANHQSSEKMSDILKGVD-----ELRSVSKNGP-------------------- 1069

  Fly   874 PVVVIAQSEDLFPEVAAEPEPQPEPVKKPDPVPETTQLTPPDVP-----LEAVPSTQLPGSSGDP 933
                .|.|:|                 |.:   :||:.:.|..|     ::.....:|..||
pombe  1070 ----YASSQD-----------------KGE---KTTEFSGPGKPNNDNYIQIASVQELDDSS--- 1107

  Fly   934 AASAGAVAAGEMSPKKSGTRIYNLSSPPDRKQTNNSSSPTLRPKPTGHLTGRGAQLINMIRNKKL 998
            ...||.:.|.:.:.::.|.                                          .||:
pombe  1108 KGKAGKMPASKKNKRQKGD------------------------------------------VKKI 1130

  Fly   999 DAASGSPYACMSTSRLVHQVTPARAQDRAEQVSTPTSELNELTGTDHTSTPIQA-PPSKDLLVFS 1062
            |.                  |...|.|..|.::||:.::|:....|.||...:| .|.|.:.|
pombe  1131 DE------------------TKNEATDMEESLTTPSGKVNKEVIVDDTSLRDEAIVPDKAIDV-- 1175

  Fly  1063 KRLPSPSASPSVSILKRKLRCESLDDVTLDSPALKRKRVSFHDPPV--SVTKEYLRDAEETRSSL 1125
                   |..|.::||..:..:|           .||..:...|.|  |.|.....:..:..|.:
pombe  1176 -------ADNSNALLKENISSQS-----------NRKADNNGTPSVNNSFTTANNDECSKENSQI 1222

  Fly  1126 KPK-RCLLMDKVAQTTEMRQALRRRGR-------------------LDSIIEIERFA-SEQ---- 1165
            :|: :....:.|..|....:..|:.||                   |:::..|||.. |||
pombe  1223 EPEGQTASREGVLSTPRSTRKKRKLGRKSQSSNVNKEVAISEVSATLENVEVIERHGISEQGQNL 1287

  Fly  1166 --TARTATTDKSLDKSTGEAPEEDA-----------------FTSLKWN--DTGNAHNISIS--- 1206
              :|...|.:.||.::  |.|||..                 |:||...  ||.|..|...|
pombe  1288 DESACVLTNESSLSQT--EIPEEKTENETTAVNGFENSKKRQFSSLLSGSIDTNNESNKVSSVEF 1350

  Fly  1207 -----EEPVKAM-EVESELETAGQDLAIMDPEAALDL 1237
                 ::.:::| |...|:|...|||...:.:...||
pombe  1351 DKSGPQDIIQSMTEATFEIEKNIQDLKSEEVQKLSDL 1387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rif1	NP_725497.1	Rif1_N	<110..240	CDD:315005	36/163 (22%)
		Atrophin-1	705..>1129	CDD:331285	77/465 (17%)
		GGN	<827..920	CDD:330621	14/97 (14%)
rif1	NP_593910.2	Rif1_N	108..471	CDD:289035	48/211 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007187
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22928
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1100
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.130