Protein Alignment CG30083 and PRSS2

DIOPT Version :10

• Sequence 1: NP_725492.3
• Gene: CG30083 / 246444
• FlyBaseID: FBgn0050083
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 72/257 - (28%)
• Similarity: 118/257 - (45%)
• Gaps: 52/257 - (20%)

  Fly    29 DISPKIMHGQNAENGTNPWM-----AYIFKYNDKEVAELVCGGTLIHKQFVLSAAHCIK------ 82
            |...||:.|...|..:.|:.     .|.|           |||:||.:|:|:||.||.|
Human    19 DDDDKIVGGYICEENSVPYQVSLNSGYHF-----------CGGSLISEQWVVSAGHCYKSAINSK 72

  Fly    83 ------RDQILAVRLGEHS------SSRYFAVTKAFRNKYFTTGSYSNDIGILRIQPIVKFNAVI 135
                  ....:.||||||:      :.::....|..|:..:.:.:..|||.::::......|:.:
Human    73 LSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRV 137

  Fly   136 RPICIITDPTKVPNVKTFK-AAGWGKT--ENETFSKVLKTVELNELNASECYNMLWVNVTESQIC 197
            ..|.:   ||..|...|.. .:|||.|  ....:...|:.::...|:.:||.......:|.:..|
Human   138 SAISL---PTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFC 199

  Fly   198 AGHPDG--DTCAGDSGGPLIHPVYMDGSLRYVQLGIIS--FGSSLCNSPGVYTRLSSFIDWI 255
            .|..:|  |:|.||||||::    .:|.|:    ||:|  :|.:..|.|||||::.:::|||
Human   200 VGFLEGGKDSCQGDSGGPVV----SNGELQ----GIVSWGYGCAQKNRPGVYTKVYNYVDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30083	NP_725492.3	Tryp_SPc	34..255	CDD:238113	68/250 (27%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	70/252 (28%)