DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30083 and CG9649

DIOPT Version :9

Sequence 1:	NP_725492.3	Gene:	CG30083 / 246444	FlyBaseID:	FBgn0050083	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_650343.1	Gene:	CG9649 / 41727	FlyBaseID:	FBgn0038211	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	77/280 - (27%)
Similarity:	130/280 - (46%)	Gaps:	45/280 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 PGAMSQF-------LEPNCGYPDI--SPKIMHGQNAENGTNPWMAYIFKYNDKEVAELVCGGTLI 69
            |...|:|       |...||...:  :|.|.:|...|.|..||||.:|::..::. ..:||||||
  Fly   228 PAQASKFYPQTIGQLSGICGREKVIQTPFIHNGIEVERGQLPWMAALFEHVGRDY-NFLCGGTLI 291

  Fly    70 HKQFVLSAAHCIK------RDQILAVRLGEH-----SSSRYFAVTKAFRNKYFTTGSYSN-DIGI 122
            ..:.|:|||||.:      ..:...|.||.:     ||.....|.:...::.:....|:: |:.:
  Fly   292 SARTVISAAHCFRFGSRNLPGERTIVSLGRNSLDLFSSGATLGVARLLIHEQYNPNVYTDADLAL 356

  Fly   123 LRIQPIVKFNAVIRPICIITDP--TKVPNVKTFKAAGWGKTE-NETFSKVLKTVELNELNASECY 184
            |::...|.....|:|||:..:.  .::|:......||||:.| ....:::.|..:.:.:...||.
  Fly   357 LQLSNHVDIGDYIKPICLWNENFLLELPSGHKSYVAGWGEDEKGNRNTRLAKMTDTDIITQWECR 421

  Fly   185 -NMLWVN---VTESQICAGHPDGD-TCAGDSGGPLI---HPVYMDGSLRYVQLGIISFGSSLCNS 241
             |:...|   :|...|||.:.... .|:|||||.|:   ..::|   ||    |::|.|..:.|.
  Fly   422 GNLSEENAKFITSHTICASNAQASGPCSGDSGGGLMLQEQDIWM---LR----GVVSAGQRMTNR 479

  Fly   242 -----PGVYTRLSSFIDWIL 256
                 |.:||.::..|:|:|
  Fly   480 CNLTLPVIYTDVAKHIEWLL 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30083	NP_725492.3	Tryp_SPc	33..255	CDD:214473	68/249 (27%)
CG30083	NP_725492.3	Tryp_SPc	34..255	CDD:238113	68/248 (27%)
CG9649	NP_650343.1	GD_N	29..124	CDD:292649
		Tryp_SPc	257..498	CDD:238113	68/248 (27%)
		Tryp_SPc	259..497	CDD:214473	67/245 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436592
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840