Protein Alignment CG30083 and TMPRSS9

DIOPT Version :10

• Sequence 1: NP_725492.3
• Gene: CG30083 / 246444
• FlyBaseID: FBgn0050083
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_001382442.1
• Gene: TMPRSS9 / 360200
• HGNCID: 30079
• Length: 1093
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 80/278 - (28%)
• Similarity: 129/278 - (46%)
• Gaps: 36/278 - (12%)

  Fly    25 CGYPD---ISPKIMHGQNAENGTNPWMAYIFKYNDKEVAELVCGGTLIHKQFVLSAAHCIKRDQ- 85
            ||...   ::.:|:.|..|..|..||.|.:     :|..|..||..:|:.::::|||||....|
Human   225 CGLQPAWRMAGRIVGGMEASPGEFPWQASL-----RENKEHFCGAAIINARWLVSAAHCFNEFQD 284

  Fly    86 -------ILAVRL-GEHSSSRYFAVTKAFRNKYFTTGSYSNDIGILRIQPIVKFNAVIRPICIIT 142
                   :.|..| |..:|:....|.:..::..:...:...|:.:|.:...:.|...|:|:|:..
Human   285 PTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPA 349

  Fly   143 DPTKVPNVKTFKAAGWGKTENETFSK--VLK--TVELNELNASECYNMLWVNVTESQICAGHPDG 203
            .....|..|....:|||..:.:...|  ||:  ||||  |:.:.|.::...::|:..:|||:.||
Human   350 ATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVEL--LDQALCASLYGHSLTDRMVCAGYLDG 412

  Fly   204 --DTCAGDSGGPLIHPVYMDGSLRYVQLGIISFGSSLCNS--PGVYTRLSSFIDWILMVVDNY-- 262
              |:|.|||||||   |..:.|.|:...||:|:|.....:  ||||.|::...||||......
Human   413 KVDSCQGDSGGPL---VCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASM 474

  Fly   263 ----TVRSPPKIQYRVWP 276
                |:...|......||
Human   475 PLAPTMAPAPAAPSTAWP 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30083	NP_725492.3	Tryp_SPc	34..255	CDD:238113	71/237 (30%)
TMPRSS9	NP_001382442.1	SEA	66..>127	CDD:460188
		LDLa	188..223	CDD:238060
		Tryp_SPc	236..465	CDD:214473	71/238 (30%)
		Tryp_SPc	538..768	CDD:238113
		Pneumo_att_G	<717..>867	CDD:114270
		Tryp_SPc	861..1087	CDD:238113