Protein Alignment CG30083 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_725492.3
• Gene: CG30083 / 246444
• FlyBaseID: FBgn0050083
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 89/287 - (31%)
• Similarity: 137/287 - (47%)
• Gaps: 55/287 - (19%)

  Fly    14 PGAMSQFLE----------------PNCGYPDI-----SPKIMHGQNAENGTNPWMAYI-FKYND 56
            |.|.||..|                .:||...:     ..:|:.|..|:.|..||:..: .||.
Human    37 PAASSQQAEAVRKRLRRRREGGAHAEDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYG- 100

  Fly    57 KEVAELVCGGTLIHKQFVLSAAHCIK--RDQIL--AVRLGEHSSSRYFAVTKAFRNK------YF 111
             .|...||||||:.:::||:||||.|  .|.::  || :|.::....:..||..:.|      .|
Human   101 -RVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAV-IGTNNIHGRYPHTKKIKIKAIIIHPNF 163

  Fly   112 TTGSYSNDIGILRIQPIVKFNAVIRPICIITDPTKV--PNVKTFKAAGWGKTENE-TFSKVLKTV 173
            ...||.|||.:..::..|::|..|:|||:..|..::  .|.|.| .:|||:|:.| ..:.:|:..
Human   164 ILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCF-ISGWGRTKEEGNATNILQDA 227

  Fly   174 ELNELNASEC-----YNMLWVNVTESQICAGHPDG--DTCAGDSGGPLIHPVYMDGSLRYVQLGI 231
            |::.::...|     |..:   :..:..|||..||  |||.|||||||:  .|:....|:..:||
Human   228 EVHYISREMCNSERSYGGI---IPNTSFCAGDEDGAFDTCRGDSGGPLM--CYLPEYKRFFVMGI 287

  Fly   232 ISFGSSLCNS---PGVYTRLSSFIDWI 255
            .|:|.. |..   ||||...|.:..|:
Human   288 TSYGHG-CGRRGFPGVYIGPSFYQKWL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30083	NP_725492.3	Tryp_SPc	34..255	CDD:238113	81/244 (33%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46		4/8 (50%)
		Tryp_SPc	78..316	CDD:238113	82/246 (33%)