Protein Alignment CG30082 and PLAT

DIOPT Version :10

• Sequence 1: NP_001188942.1
• Gene: CG30082 / 246443
• FlyBaseID: FBgn0050082
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_000921.1
• Gene: PLAT / 5327
• HGNCID: 9051
• Length: 562
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 93/291 - (31%)
• Similarity: 141/291 - (48%)
• Gaps: 56/291 - (19%)

  Fly    18 KLRAQFID-PNCGTTINL----PPTNRIVGGRTADIGSNPWLAYL---HKNS---SLVCTGTLIT 71
            :|..::.| |:| :|..|    .|..||.||..|||.|:||.|.:   |:.|   ..:|.|.||:
Human   285 RLTWEYCDVPSC-STCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILIS 348

  Fly    72 KRFVLTAAHCLHSF---HLLTVRLGEYDTSTRIDCTSEFCIPTYEE--YSVENAYIHTFFGGRQD 131
            ..::|:||||....   |.|||.||.   :.|:       :|..||  :.||...:|..|.  .|
Human   349 SCWILSAAHCFQERFPPHHLTVILGR---TYRV-------VPGEEEQKFEVEKYIVHKEFD--DD 401

  Fly   132 S-RNDIGLLKLNG----TVVYKLFIRPICLFRDPGQVPYSSTYEAAGWGKIDLINT--ATVLQTV 189
            : .|||.||:|..    .......:|.:||.....|:|..:..|.:|:||.:.::.  :..|:..
Human   402 TYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEA 466

  Fly   190 NLIRLDQSDC--ERSLRTSLSYGQFCAGQWRA--------DTCSGDSGGPLSRKMSNGRITRTVQ 244
            ::.....|.|  :..|..:::....|||..|:        |.|.|||||||. .:::||:|   .
Human   467 HVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLV-CLNDGRMT---L 527

  Fly   245 LGIVSYGHYLCRG----PGVYTYVPSFTNWI 271
            :||:|:|  |..|    |||||.|.::.:||
Human   528 VGIISWG--LGCGQKDVPGVYTKVTNYLDWI 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30082	NP_001188942.1	Tryp_SPc	40..274	CDD:238113	85/264 (32%)
PLAT	NP_000921.1	FN1	41..83	CDD:214494
		Important for binding to annexin A2	42..52
		EGF	86..117	CDD:394967
		KR	125..209	CDD:238056
		Kringle	215..296	CDD:395005	3/10 (30%)
		Tryp_SPc	313..559	CDD:238113	84/262 (32%)