Protein Alignment CG30082 and HPN

DIOPT Version :10

• Sequence 1: NP_001188942.1
• Gene: CG30082 / 246443
• FlyBaseID: FBgn0050082
• Length: 280
• Species: Drosophila melanogaster
• Sequence 2: NP_002142.1
• Gene: HPN / 3249
• HGNCID: 5155
• Length: 417
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 87/299 - (29%)
• Similarity: 116/299 - (38%)
• Gaps: 75/299 - (25%)

  Fly    13 VCLTPKLRAQF---IDPNCGTTINLPPTNRIVGGRTADIGSNPWLAYLHKNSSLVCTGTLITKRF 74
            ||..|  |.:|   |..:||.  ...|.:||||||...:|..||...|..:.:.:|.|:|::..:
Human   137 VCDCP--RGRFLAAICQDCGR--RKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDW 197

  Fly    75 VLTAAHCL----------------------HSFHL---LTVRLGEYDTSTRIDCTSEFCIPTYEE 114
            |||||||.                      |...|   ..|..|.|             :|..:.
Human   198 VLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGY-------------LPFRDP 249

  Fly   115 YSVENAYIHTFFGGRQDSRNDIGLLKLNGTVVYKLFIRPICLFRDPGQVPYSSTYEAAGWGKIDL 179
            .|.||:             |||.|:.|:..:....:|:|:||......:.........|||
Human   250 NSEENS-------------NDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWG---- 297

  Fly   180 INT------ATVLQTVNLIRLDQSDCERS--LRTSLSYGQFCAG--QWRADTCSGDSGGPLSRKM 234
             ||      |.|||...:..:....|..:  ....:....||||  :...|.|.||||||...:.
Human   298 -NTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCED 361

  Fly   235 SNGRITRTVQLGIVSYGH--YLCRGPGVYTYVPSFTNWI 271
            |..|..|....||||:|.  .|.:.|||||.|..|..||
Human   362 SISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30082	NP_001188942.1	Tryp_SPc	40..274	CDD:238113	77/269 (29%)
HPN	NP_002142.1	Hepsin-SRCR	51..159	CDD:462736	8/25 (32%)
		Tryp_SPc	163..400	CDD:238113	75/267 (28%)