DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30082 and CG30091

DIOPT Version :9

Sequence 1:	NP_001188942.1	Gene:	CG30082 / 246443	FlyBaseID:	FBgn0050082	Length:	280	Species:	Drosophila melanogaster
Sequence 2:	NP_725484.1	Gene:	CG30091 / 246449	FlyBaseID:	FBgn0050091	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	106/278 - (38%)
Similarity:	147/278 - (52%)	Gaps:	20/278 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 WIASFAFLVCLTPKLRAQFIDPNCGTTINLPPTNRIVGGRTADIGSNPWLAYLHKNSSLVCTGTL 69
            |:..||::: ...:..|:.:|.:||..:.|.|  :||||..|....|||:|.:..|...:|.|::
  Fly     5 WVVLFAWML-TAGRGSARLLDEDCGVPMQLIP--KIVGGVDAGELKNPWMALIKTNDEFICGGSV 66

  Fly    70 ITKRFVLTAAHCLHS-------FHLLTVRLGEYDTSTRIDCTSEFCIPTYEEYSVENAYIHTFFG 127
            ||.:||||||||:.:       :..|||.||.|    .:..|.|...| :|.|:||..|||..|
  Fly    67 ITNKFVLTAAHCMCTDEECIVKYTQLTVTLGVY----HLLATGEHNHP-HEIYNVERVYIHDSF- 125

  Fly   128 GRQDSRNDIGLLKLNGTVVYKLFIRPICLFRDPGQVPYS---STYEAAGWGKIDLINTATVLQTV 189
            ..|:.||||.||:|..::|||..|:|:|:..:....|.:   ..:.|.|||.......:..||.|
  Fly   126 AIQNYRNDIALLRLQKSIVYKPQIKPLCILLNDQLKPQTDLIQEFTAIGWGVTGNGKMSNNLQMV 190

  Fly   190 NLIRLDQSDCERSLRTSLSYGQFCAG-QWRADTCSGDSGGPLSRKMSNGRITRTVQLGIVSYGHY 253
            .:.|:|:..||.:...:..|..|||| ....|||..||||||...|....|.|..||||||.|..
  Fly   191 KIYRIDRKMCEAAFWYTFDYPMFCAGTAVGRDTCKRDSGGPLYIHMLFDGIKRATQLGIVSTGTE 255

  Fly   254 LCRGPGVYTYVPSFTNWI 271
            .|||.|:||.|....::|
  Fly   256 DCRGFGMYTDVMGHIDFI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30082	NP_001188942.1	Tryp_SPc	39..271	CDD:214473	96/242 (40%)
CG30082	NP_001188942.1	Tryp_SPc	40..274	CDD:238113	97/243 (40%)
CG30091	NP_725484.1	Tryp_SPc	36..273	CDD:214473	96/242 (40%)
		Tryp_SPc	37..276	CDD:238113	97/243 (40%)
		Trypsin	310..520	CDD:278516
		Tryp_SPc	313..520	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463345
Domainoid	1	1.000	102	1.000	Domainoid score	I4289
eggNOG	1	0.900	-	-		E33208_3BQ4K
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.640