DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir51b and Ir7e

DIOPT Version :9

Sequence 1:	NP_725440.1	Gene:	Ir51b / 246442	FlyBaseID:	FBgn0050081	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001138176.1	Gene:	Ir7e / 7354417	FlyBaseID:	FBgn0259189	Length:	608	Species:	Drosophila melanogaster

Alignment Length:	609	Identity:	120/609 - (19%)
Similarity:	219/609 - (35%)	Gaps:	152/609 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 NDLIIWLHQTMGVTSLTMNLFLQ--PEHIRP-LGHFKITRYNGIALF-----------FCHDKHD 106
            |.::..|.:..|:..|.:...|:  |.|..| ..||.:...:..|.|           :.:::|.
  Fly    60 NKMMSTLFREWGLAPLQIVNVLRGVPWHPVPGRRHFNVIFTDSFAAFEEIRMEYYSREYNYNEHY 124

  Fly   107 IMWLTLDRNLRKLRRIRLIIILRNQRSGSQGAIKSIFNALWQYQFLNVLV-LQRDQ----LYSYT 166
            .::|.        .|.||:          ||.::.||:..|:|:.::..: :|:..    .|||.
  Fly   125 FIFLQ--------ARDRLL----------QGEMRLIFDYCWRYRLIHCSIQVQKSNGDILFYSYY 171

  Fly   167 PY----------PAMRFFKLDIHTEP-LFPHAARNFHGYVVSTPAENDIPRVFHVHDPLTKSRKV 220
            |:          ..:..:...:..|| |||...|||.|..:.. |..|:|....:.:...:..:|
  Fly   172 PFGEHGCSDMEPQLINRYNGSMLVEPDLFPRKLRNFFGCPLRC-ALWDVPPFLTLDEDQEEVLRV 235

  Fly   221 L-GYAYRTFVEYLDHYNASL-----RLTNPDENLD----PTTSVNMNHIVQLIIDGQLEISLHPY 275
            . ||..|..:...:..|.::     .:...||.|:    ....:.:..|.|.:..|.:..|.|.|
  Fly   236 NGGYEGRLLLALAEKMNFTIAVRKVHVNMRDEALEMLRRDEVDLTLGGIRQTVARGMVATSSHNY 300

  Fly   276 --------VFTPPTATKSYPLLIYPNCLIVPMRNEIPRHMYLLRPFQLYSWYILLFAVFYITGIL 332
                    |........|:.:|.|                    |::|..|..:| .|..::.::
  Fly   301 HQTREVFGVLASSYELSSFDILFY--------------------PYRLQIWMGIL-GVVALSALI 344

  Fly   333 YCISPKLNKSSWPQRLGLNFLDAISKILFISPPI------------------------TIYRPTW 373
            ..|..::.:.....|..||.     :::|:..|:                        |||:...
  Fly   345 QLIVGRMLRERMGSRFWLNL-----ELVFVGMPLLECPRSHTARLYCVMLMMYTLIIRTIYQGLL 404

  Fly   374 RHLIIFLQLSVLGFMSTSW-YNIE--LDSFFTTI---VVGEQVNSMDQLVHQQQRVLVKEYEINT 432
            .|||...||:       .| ..||  :...||.:   :|.|.::.:..:.|.:.|:|....|::.
  Fly   405 YHLIRTHQLN-------RWPQTIESLVQKNFTVVLTPIVQEVLDEIPSVQHMRFRLLEANSELDP 462

  Fly   433 FLRHVEPRLVEKVSRLLVPVNASEQVSALLSFNRSFAYPFTEERWQFFAMQQQYAFKPIFRFSSA 497
            ..      .:|...:|...|.|| .:...:.|||..|....:...|......:...:.|......
  Fly   463 LY------FLEANHQLRQHVTAS-ALDIFIHFNRLSADKVHQRGEQGSGAHFEIVPEDIISMQLT 520

  Fly   498 CLGSPHIGYPMRVDSHLETSLNHFILKIQDTGLLNHWVVSDFNDAMRAGYVRFVDNVLGYQSIDV 562
            ...:.|        |.|...||..|:.::..|||:.|...:.:::    |:|   |...:|.:..
  Fly   521 MYLAKH--------SFLIDQLNEEIMWMRSVGLLSVWSRWELSES----YLR---NEQSFQVLGT 570

  Fly   563 DTLRLGWCVLGIGWILSALVFSCE 586
            ..|...:.::.:|.|:..|||..|
  Fly   571 MELYAIFLMVLVGLIVGLLVFILE 594

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir51b	NP_725440.1	None
Ir7e	NP_001138176.1	PBPb	218..>313	CDD:214497	17/94 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010