DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir51b and Ir56d

DIOPT Version :9

Sequence 1:	NP_725440.1	Gene:	Ir51b / 246442	FlyBaseID:	FBgn0050081	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_611432.1	Gene:	Ir56d / 37252	FlyBaseID:	FBgn0034458	Length:	632	Species:	Drosophila melanogaster

Alignment Length:	606	Identity:	163/606 - (26%)
Similarity:	279/606 - (46%)	Gaps:	51/606 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 TNAAYNVTLLKS--VLSLISTREPWINTPIFVGHNTQGGDLN--DLIIWLHQTMGVTSLTMNLFL 77
            ||.:.|:|||.:  ||.:........:...|:.:.::..|||  |...:.|.......:..||.:
  Fly    18 TNGSDNITLLNNMFVLEMFYRITQLYHFKNFIFYISERLDLNNKDSQEFFHNFWTYFPMAPNLII 82

  Fly    78 QPEHIRPLGHFKITRYNGIALFFCHDKHDIMWLTLDRNLRKLRRIRLIIIL----------RNQR 132
            ..||...:...:......:.:.|...|.|.:......|.:.:..::.|.:|          .|..
  Fly    83 TREHHLGIPMMQFISTPSLVMVFTTGKDDPIMELASHNQQGIHWLKTIFVLFPSLQSRDFETNPE 147

  Fly   133 SGSQ--GAIKSIFNALWQYQFLNV-LVLQRDQLYSYTPYPAMRFF-KLDI-HTEPLFPHAARNFH 192
            |.:|  ..||.:::.:|:.||:|. |:..:|.::...|||..... |..: ..|..|...|:|..
  Fly   148 SLAQFTAEIKDVYDWVWRKQFINTFLITIKDNVFILDPYPTPSIVNKTGVWQAEEFFHKYAKNMK 212

  Fly   193 GYVVSTPAENDIPRVFHVHDPLTKSRK--VLGYAYRTFVEYLDHYNASLRLTNPDENLDPTTSVN 255
            ||:|.||...|:||||....|..:..|  :.|.:...|:.:|:..||:|..|:.:...|   .:|
  Fly   213 GYLVRTPILYDMPRVFKSDRPTNRYEKNFIHGTSGNLFLGFLEFVNATLMDTSANVTAD---YLN 274

  Fly   256 MNHIVQLIIDGQLEISLHPY--VFTPPTATKSYPLLIYPNCLIVPMRNEIPRHMYLLRPFQLYSW 318
            |.:::.|:..|..|..:|.:  :.|....:.|||:.|...|::||.||:.|...|:....|...|
  Fly   275 MTNLLDLVSQGVYETLIHSFTEITTKFVVSYSYPIGINDCCIMVPYRNQSPADQYMHEALQENVW 339

  Fly   319 YILLFAVFYITGILYCISPKLNKSSWPQRLGLNFLDAISKILFISPPITIYRPTWRHLIIFLQLS 383
            .::.....|||..:|..||..     |:.|...||.:|..:.:..|...|..||.|...:::.|:
  Fly   340 VLISLFTLYITVAIYLCSPLR-----PRDLSAAFLQSICTLTYSVPTFIIRTPTLRMRYLYILLA 399

  Fly   384 VLGFMSTSWYNIELDSFFTTIVVGEQVNSMDQLVHQQQRV--LVKEYE--INTFLRHVEPRL--V 442
            :.|.::::.|...:.|:|||.....|:|::..:|....|:  |..|||  ..:.|::.|..|  |
  Fly   400 IWGIVTSNLYISRMTSYFTTAPPVRQINTVQDVVEANLRIKMLAIEYERMAKSPLQYPESYLNQV 464

  Fly   443 EKVSRLLVPVNASEQVSALLSFNRSFAYPFTEERWQFFAMQQQYAFKPIFRFSSACLGSPHIGYP 507
            :.|.:.::.::..       .||.||.|..:.:||:|..:||.:..|||||.:..|.|..:..:|
  Fly   465 DLVDKHMLDLHRD-------PFNTSFGYTVSSDRWRFLNLQQLHLRKPIFRLTEICEGPFYHVFP 522

  Fly   508 MRVDSHLETSLNHFILKIQDTGLLNHWVVSDFNDAMRAG--YVRFVDNVLGYQSID-VDTLRLGW 569
            :..|||:.:.:..:|:..|..||:|||....|.:|:...  :|...|:.....|:| ..:|...|
  Fly   523 LHKDSHMRSVMTEYIMIAQQAGLMNHWERETFWEAVHLHRIHVHLFDDEPMALSLDFFSSLLRTW 587

  Fly   570 CVLGIGWILSALVFSCEY-WH 589
            .   :|.||:.|.|:.|. ||
  Fly   588 T---LGLILAGLAFAAEMKWH 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir51b	NP_725440.1	None
Ir56d	NP_611432.1	ATPase-IIIA_H	<312..422	CDD:273731	32/114 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CJJD
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001038
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910