DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30075 and fkbp8

DIOPT Version :9

Sequence 1:	NP_725390.1	Gene:	CG30075 / 246437	FlyBaseID:	FBgn0050075	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_957178.1	Gene:	fkbp8 / 393858	ZFINID:	ZDB-GENE-040426-1849	Length:	406	Species:	Danio rerio

Alignment Length:	183	Identity:	39/183 - (21%)
Similarity:	71/183 - (38%)	Gaps:	40/183 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QSLSSDEQDDI--------FFLIYRKAHTLFQAGKLWMRRMRYHDAQRAFEKA--ITRLKTCKTS 84
            |.||:||..|:        ..|..||.    :.|.:..:|..|..|..::..|  ||...:....
Zfish   192 QLLSADEALDLELMPPSERIILANRKR----ERGNVHYQRADYAFAVNSYGIALQITEASSRVDI 252

  Fly    85 SFEQQCRKKDMLIALFESLMICFNKMRQSR------------CVCYVMKELRLLTINNPSALALC 137
            |.|::....||.:.       |.|.|..::            ||       .:|.....:..||.
Zfish   253 SQEEEEELLDMKVK-------CLNNMAAAQLKLDHYEAALRSCV-------SVLAHQPDNVKALF 303

  Fly   138 QHGRALSDLGKYHPSRLCYIKALKKRPRDQGIKDKITRISKRITELEDTNQML 190
            :.|:.|:..|::..:......|||..|.::.|..:::::.|:.:|.:...|.:
Zfish   304 RKGKVLALQGEFAEAIKTLKMALKLEPSNKTIHAELSKLVKKHSEQKGAEQAM 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30075	NP_725390.1	None
fkbp8	NP_957178.1	FKBP_C	106..194	CDD:278674	1/1 (100%)
		TPR_11	214..296	CDD:290150	19/99 (19%)
		TPR repeat	214..259	CDD:276809	11/48 (23%)
		TPR repeat	265..293	CDD:276809	5/41 (12%)
		TPR_11	266..330	CDD:290150	14/77 (18%)
		TPR repeat	298..328	CDD:276809	7/29 (24%)
		TPR_1	299..332	CDD:278916	9/32 (28%)
		TPR repeat	333..361	CDD:276809	4/24 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810