DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30075 and Fkbp5

DIOPT Version :9

Sequence 1:	NP_725390.1	Gene:	CG30075 / 246437	FlyBaseID:	FBgn0050075	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	XP_006256284.1	Gene:	Fkbp5 / 361810	RGDID:	1309155	Length:	473	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	39/177 - (22%)
Similarity:	75/177 - (42%)	Gaps:	25/177 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KGFKAAKNDKFSTHALLNENDNDQSLSSDEQDDIFFLIYRKAHTLFQAGKLWMRRMRYHDAQRAF 71
            |.|:.||...        |.|..:.|   ||..|   :..|....|:.||       |..|...:
  Rat   265 KSFEKAKESW--------EMDTKEKL---EQAAI---VKEKGTVYFKGGK-------YMQAVIQY 308

  Fly    72 EKAITRLKTCKTSSFEQQCRKKDMLIALFESLMICFNKMRQ-SRCVCYVMKELRLLTINNPSALA 135
            .|.::.|:.....|.::....:..|:|.|.:|.:|:.|:|: ::.|....|.|.|.:.|..   .
  Rat   309 GKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEK---G 370

  Fly   136 LCQHGRALSDLGKYHPSRLCYIKALKKRPRDQGIKDKITRISKRITE 182
            |.:.|.|...:.::..::..:.|.|:..|:::..:.:|:...::..|
  Rat   371 LYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISVCQRKAKE 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30075	NP_725390.1	None
Fkbp5	XP_006256284.1	FKBP_C	61..152	CDD:278674
		TPR_11	284..364	CDD:290150	21/89 (24%)
		TPR repeat	285..313	CDD:276809	8/37 (22%)
		TPR_11	336..399	CDD:290150	15/65 (23%)
		TPR	336..367	CDD:197478	9/30 (30%)
		TPR repeat	336..362	CDD:276809	7/25 (28%)
		TPR repeat	367..397	CDD:276809	6/32 (19%)
		TPR_1	369..401	CDD:278916	6/34 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900