DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30075 and fkbp4

DIOPT Version :9

Sequence 1:	NP_725390.1	Gene:	CG30075 / 246437	FlyBaseID:	FBgn0050075	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	XP_005173673.1	Gene:	fkbp4 / 321795	ZFINID:	ZDB-GENE-030131-514	Length:	450	Species:	Danio rerio

Alignment Length:	196	Identity:	34/196 - (17%)
Similarity:	87/196 - (44%)	Gaps:	20/196 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KKGFKAAKNDKFS--THALL---------NENDNDQSLSSDEQDDIFFLIYRKAHTLFQAGKLWM 59
            |.||..|.::|::  .:|.|         .:......:::.|:.:...::..|....|:.||
Zfish   219 KYGFGTAGSEKYNIPPNATLQYKIKMKAFEKAKESWEMNTIEKLEQSVIVKEKGTQYFKEGK--- 280

  Fly    60 RRMRYHDAQRAFEKAITRLKTCKTSSFEQQCRKKDMLIALFESLMICFNKMRQSRCVCYVMKELR 124
                |..|...:::.::.|:...:...:.:.:.|.:.:|.:.:|.:|:.|::.:........:..
Zfish   281 ----YKQAIVQYKRIVSWLEHESSMQPDDEEKAKALRLAAYLNLAMCYLKLQDANPALENCDKAL 341

  Fly   125 LLTINNPSALALCQHGRALSDLGKYHPSRLCYIKALKKRPRDQGIKDKITRISKRITELEDTNQM 189
            .|..||..  ||.:.|.||..:.::..:::.:.:.::..|.::..|.:|:...|.:.|..:.::.
Zfish   342 ELDANNEK--ALFRRGEALVVMKEFDMAKVDFQRVIELYPANKAAKSQISICQKHMREQHEKDKR 404

  Fly   190 L 190
            |
Zfish   405 L 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30075	NP_725390.1	None
fkbp4	XP_005173673.1	FKBP_C	38..129	CDD:278674
		ppisom_GldI	<153..249	CDD:132555	7/29 (24%)
		TPR repeat	269..293	CDD:276809	6/30 (20%)
		TPR_16	270..348	CDD:290168	14/84 (17%)
		TPR repeat	305..343	CDD:276809	5/37 (14%)
		TPR_11	316..379	CDD:290150	11/64 (17%)
		TPR_1	316..347	CDD:278916	4/30 (13%)
		TPR repeat	348..376	CDD:276809	5/29 (17%)
		TPR_1	349..381	CDD:278916	6/33 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810