DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30075 and FKBP8

DIOPT Version :9

Sequence 1:	NP_725390.1	Gene:	CG30075 / 246437	FlyBaseID:	FBgn0050075	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_036313.3	Gene:	FKBP8 / 23770	HGNCID:	3724	Length:	413	Species:	Homo sapiens

Alignment Length:	154	Identity:	33/154 - (21%)
Similarity:	65/154 - (42%)	Gaps:	19/154 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 QAGKLWMRRMRYHDAQRAFEKAITRLKTCKTSS------FEQQCRKKDMLIALFESLMICFNKMR 111
            :.|....:|..:..|..:::.||..:    |||      ||::.:...:.:....:|.....|:.
Human   227 ECGNAHYQRADFVLAANSYDLAIKAI----TSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLD 287

  Fly   112 QSRCVCYVMKELRLLTINNPSAL-ALCQHGRALSDLGKYHPSRLCYIKALKKRPRDQGIKDKITR 175
            ..|.   .::...|:..:.|..: ||.:.|:.|:..|:|..:......|||..|.::.|..::::
Human   288 HYRA---ALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSK 349

  Fly   176 ISK-----RITELEDTNQMLSQLS 194
            :.|     |.||.....:||...|
Human   350 LVKKHAAQRSTETALYRKMLGNPS 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30075	NP_725390.1	None
FKBP8	NP_036313.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..68
		FKBP_C	113..202	CDD:278674
		TPR_11	222..304	CDD:290150	14/83 (17%)
		TPR 1	222..255		6/31 (19%)
		TPR repeat	231..267	CDD:276809	9/39 (23%)
		TPR repeat	272..302	CDD:276809	4/32 (13%)
		TPR 2	273..306		5/35 (14%)
		TPR_11	274..338	CDD:290150	14/66 (21%)
		TPR 3	307..340		10/32 (31%)
		TPR	307..340	CDD:197478	10/32 (31%)
		TPR repeat	307..335	CDD:276809	7/27 (26%)
		TPR repeat	341..369	CDD:276809	5/27 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810