DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30075 and FKBP4

DIOPT Version :9

Sequence 1:	NP_725390.1	Gene:	CG30075 / 246437	FlyBaseID:	FBgn0050075	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_002005.1	Gene:	FKBP4 / 2288	HGNCID:	3720	Length:	459	Species:	Homo sapiens

Alignment Length:	178	Identity:	34/178 - (19%)
Similarity:	74/178 - (41%)	Gaps:	12/178 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KKGFKAAKND--KFSTHALLNENDNDQ-SLSSDEQDDIFFLIYRKAHTLFQAGKLWMRRMRYHDA 67
            |:.|:...|.  |:..|....|...:. .::|:|:.:...::..:....|:.||       |..|
Human   232 KEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGK-------YKQA 289

  Fly    68 QRAFEKAITRLKTCKTSSFEQQCRKKDMLIALFESLMICFNKMRQSRCVCYVMKELRLLTINNPS 132
            ...::|.::.|:...:.|.|:..:.:.:.:|...:|.:|..|::..........:...|..||..
Human   290 LLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEK 354

  Fly   133 ALALCQHGRALSDLGKYHPSRLCYIKALKKRPRDQGIKDKITRISKRI 180
              .|.:.|.|...:..:..:|..:.|.|:..|.::..|.::....:||
Human   355 --GLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRI 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30075	NP_725390.1	None
FKBP4	NP_002005.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
		FKBP_C	43..134	CDD:306713
		FKBP_N	<155..254	CDD:332399	5/21 (24%)
		TPR_11	<250..>395	CDD:330823	27/153 (18%)
		Interaction with tubulin. /evidence=ECO:0000250	267..400		24/141 (17%)
		TPR repeat	274..301	CDD:276809	6/33 (18%)
		TPR repeat	306..348	CDD:276809	6/41 (15%)
		TPR repeat	353..381	CDD:276809	5/29 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	421..459
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810