DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30075 and Fkbp8

DIOPT Version :9

Sequence 1:	NP_725390.1	Gene:	CG30075 / 246437	FlyBaseID:	FBgn0050075	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001104536.1	Gene:	Fkbp8 / 14232	MGIID:	1341070	Length:	403	Species:	Mus musculus

Alignment Length:	216	Identity:	45/216 - (20%)
Similarity:	88/216 - (40%)	Gaps:	34/216 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLPNDKK---GFKAAKNDKFSTHALL---------NENDNDQSLSSDEQDDIFFLIYRKAHTLFQ 53
            |:..|.|   |.:.:::.....||.|         .:..:.:.||..|:   ..|..||.    :
Mouse   160 MVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAEDGPDLEMLSGQER---VALANRKR----E 217

  Fly    54 AGKLWMRRMRYHDAQRAFEKAITRLKTCKTSSFEQQCRKKDMLIALFESLMICFNKMRQSRC-VC 117
            .|....:|..:..|..:::.||..:.:  .:..:..|.:::.|:.|   .:.|.|.:..|:. :.
Mouse   218 CGNAHYQRADFVLAANSYDLAIKAITS--NTKVDMTCEEEEELLQL---KVKCLNNLAASQLKLD 277

  Fly   118 YVMKELR----LLTINNPSALALCQHGRALSDLGKYHPSRLCYIKALKKRPRDQGIKDKITRISK 178
            :....||    :|.....:..||.:.|:.|:..|:|..:......|||..|.::.|..:::::.|
Mouse   278 HYRAALRSCSQVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVK 342

  Fly   179 -----RITELEDTNQMLSQLS 194
                 |.||.....:||...|
Mouse   343 KRAAQRSTETALYRKMLGNPS 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30075	NP_725390.1	None
Fkbp8	NP_001104536.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	28..54
		FKBP_C	103..192	CDD:365980	7/31 (23%)
		TPR	<206..329	CDD:223533	27/134 (20%)
		TPR 1	212..245		7/38 (18%)
		TPR repeat	245..292	CDD:276809	9/49 (18%)
		TPR 2	263..296		6/32 (19%)
		TPR 3	297..330		10/32 (31%)
		TPR repeat	297..325	CDD:276809	7/27 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900