DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30075 and FKBP9

DIOPT Version :9

Sequence 1:	NP_725390.1	Gene:	CG30075 / 246437	FlyBaseID:	FBgn0050075	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001271270.1	Gene:	FKBP9 / 11328	HGNCID:	3725	Length:	623	Species:	Homo sapiens

Alignment Length:	164	Identity:	31/164 - (18%)
Similarity:	66/164 - (40%)	Gaps:	51/164 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ALLNENDNDQSLSSDEQDDIFFLIYRKAHTLFQAGKLWMRRMRYH------DAQRAFEKAITRLK 79
            |||:.::...|:|.:.:     ::......:.|:|..    :|||      |. ..|:.:.:|.:
Human   302 ALLDLHNPKDSISIENK-----VVPENCERISQSGDF----LRYHYNGTLLDG-TLFDSSYSRNR 356

  Fly    80 TCKTSSFEQQCRKKDMLIALFESLM-ICFNKMRQSRCV------------------CYVMKELRL 125
            |     |:....:..::..:.|.|: :|..:.|  |.|                  ..::.::.:
Human   357 T-----FDTYIGQGYVIPGMDEGLLGVCIGEKR--RIVVPPHLGYGEEGRGNIPGSAVLVFDIHV 414

  Fly   126 LTINNPS-ALALCQHGR-----ALSDLG---KYH 150
            :..:||| ::::..|.:     .||..|   |||
Human   415 IDFHNPSDSISITSHYKPPDCSVLSKKGDYLKYH 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30075	NP_725390.1	None
FKBP9	NP_001271270.1	FKBP_C	47..191	CDD:278674
		FKBP_C	212..304	CDD:278674	1/1 (100%)
		FKBP_C	324..415	CDD:278674	16/102 (16%)
		FKBP_C	435..527	CDD:278674	6/14 (43%)
		EF-hand_7	548..612	CDD:290234
		EFh	550..611	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900