DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30060 and PEBP4

DIOPT Version :9

Sequence 1:	NP_725293.1	Gene:	CG30060 / 246426	FlyBaseID:	FBgn0265272	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	NP_001350162.1	Gene:	PEBP4 / 157310	HGNCID:	28319	Length:	227	Species:	Homo sapiens

Alignment Length:	154	Identity:	45/154 - (29%)
Similarity:	70/154 - (45%)	Gaps:	20/154 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 QPIIRF--KADPEHYHTLMMVDLDVPPDNNTE-----WLIWMVGNIPGCDV----AMGQTLVAYD 113
            :||::|  ..|...| .|:|||.|.|  :..|     |..|:|.:|.|.|:    ..||.|.||.
Human    76 EPIVKFPGAVDGATY-ILVMVDPDAP--SRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQ 137

  Fly   114 NRRTIHGSNIHRIVFLAFKQYLELDFDETFVPEGEEKGRGTFNCHNFARKYALGNPMAANFYLVE 178
            .......|..||..|..   ||:.....:.:|: |.|.||::....|..::.||.|.|:..::.:
Human   138 APSPPAHSGFHRYQFFV---YLQEGKVISLLPK-ENKTRGSWKMDRFLNRFHLGEPEASTQFMTQ 198

  Fly   179 WLWRWTPTYLV-SEHEFEPSNGNE 201
             .::.:||... .|...||.:.|:
Human   199 -NYQDSPTLQAPRERASEPKHKNQ 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30060	NP_725293.1	PEBP_euk	34..177	CDD:176644	39/127 (31%)
PEBP4	NP_001350162.1	PEBP_euk	46..197	CDD:176644	39/127 (31%)
		Important for secretion. /evidence=ECO:0000269\|PubMed:27033522	188..227		8/35 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	202..227		6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1557122at2759
OrthoFinder	1	1.000	-	-		FOG0000438
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11362
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X275
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020