DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG30060 and ATP8B3

DIOPT Version :9

Sequence 1:	NP_725293.1	Gene:	CG30060 / 246426	FlyBaseID:	FBgn0265272	Length:	202	Species:	Drosophila melanogaster
Sequence 2:	XP_006722717.1	Gene:	ATP8B3 / 148229	HGNCID:	13535	Length:	1310	Species:	Homo sapiens

Alignment Length:	206	Identity:	42/206 - (20%)
Similarity:	71/206 - (34%)	Gaps:	61/206 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LKRHHVIPR-LFACKPTKVISVLYPCDIDI--------KPGIMVVINE--TLK-----QPIIRFK 66
            |::.:::|. :.....|:..|:.|...:||        :..:||...|  |:|     |..:..:
Human   243 LRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCE 307

  Fly    67 ADPEHYHTLMMVDLDVPPDNNTEW----LIWMVGN--IPGC-----DVAMGQTLVA-YDNRRTIH 119
            |.....|..:         ...||    ....:||  :.||     |...|..:.| :|.:...:
Human   308 APNSRMHHFV---------GCLEWNDKKYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKN 363

  Fly   120 GSNIH-----------RIVFLAFKQY----LELDFDETF-VPEGEEKGRGTFNCHNFARKYALGN 168
            ...||           ::|.:.|...    |.|.|...| |.|        |..|::......|:
Human   364 CGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKE--------FKDHHYYLSGVHGS 420

  Fly   169 PMAANFYLVEW 179
            .:||..:.|.|
Human   421 SVAAESFFVFW 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30060	NP_725293.1	PEBP_euk	34..177	CDD:176644	37/185 (20%)
ATP8B3	XP_006722717.1	PhoLip_ATPase_N	108..184	CDD:292826
		ATPase-Plipid	133..1220	CDD:273734	42/206 (20%)
		Cation_ATPase	<593..669	CDD:289987
		HAD_like	<931..975	CDD:304363
		PhoLip_ATPase_C	975..1220	CDD:292829
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0206
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900