DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30059 and Sulf2

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001239508.1	Gene:	Sulf2 / 72043	MGIID:	1919293	Length:	908	Species:	Mus musculus

Alignment Length:	490	Identity:	172/490 - (35%)
Similarity:	243/490 - (49%)	Gaps:	79/490 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PNILLILSDDQDVELRGMFPMEHTIEMLGFGGALFHNAYTPSPICCPARTSLLTGMYAHNHGTRN 88
            |||:|:|:|||||||..|..|..|..::..|||.|.||:..:|:|||:|:|:|||.|.|||.|..
Mouse    77 PNIILVLTDDQDVELGSMQVMNKTRRIMEQGGAHFINAFVTTPMCCPSRSSILTGKYVHNHNTYT 141

  Fly    89 NSVSGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLNQYWGAGDVPKGWNNFYGLHGNSRYY 153
            |:.:  |..|.|:...|.|.....|...||.|.|.|||||:|.|: .||.||..:.||..|||:|
Mouse   142 NNEN--CSSPSWQAQHESRTFAVYLNSTGYRTAFFGKYLNEYNGS-YVPPGWKEWVGLLKNSRFY 203

  Fly   154 NYTL-----RENTGNVHYESTYLSDLLRDRAADFLRNATQ--SSEPFFAMVAPPAAHEPFTPAPR 211
            ||||     :|..|: .|.:.||:||:.:.:..|.|.:.:  ...|...:::..|.|.|...||:
Mouse   204 NYTLCRNGVKEKHGS-DYSTDYLTDLITNDSVSFFRTSKKMYPHRPVLMVISHAAPHGPEDSAPQ 267

  Fly   212 HEGVFSHIEALRTPSFNQV-KQDKHWLVR---AARRLPNETINTIDTYFQKRWETLLAVDELVVT 272
            :..:|.:.....|||:|.. ..||||::|   ..:.:..|..|.:.   :||.:||::||:.:.|
Mouse   268 YSRLFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQ---RKRLQTLMSVDDSMET 329

  Fly   273 LMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVPLLIRGPGIAPESHIDTAVS 337
            :..:|.:|..|:||||:||:|:|||:|||.....|..|||.||.||..:|||.:...|.....|.
Mouse   330 IYDMLVETGELDNTYILYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYVRGPNVEAGSLNPHIVL 394

  Fly   338 LVDLAPTILAWADIDTPSYMDGQSFHELLLNKRRRVPFFERSLLIEYWGEGTLATFNPECPWPEK 402
            .:|||||||..|.:|.|:.|||:|..: ||:..|.|..|.....:..|.:..|.         |:
Mouse   395 NIDLAPTILDIAGLDIPADMDGKSILK-LLDSERPVNRFHLKKKLRVWRDSFLV---------ER 449

  Fly   403 DRLAQCTPAADCHCQDAWNNTYACLRNIRHRE-DRIYCEFRDNENFLEAYDLQLDPFQMTNIAYD 466
            .:|                        :..|| |::..:   .||||..|....|..|
Mouse   450 GKL------------------------LHKREGDKVNAQ---EENFLPKYQRVKDLCQ------- 480

  Fly   467 LLPIERALYSLRLKNLTQ-------CSG----HSC 490
                 ||.|....:.|.|       .||    |.|
Mouse   481 -----RAEYQTACEQLGQKWQCVEDASGTLKLHKC 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	163/454 (36%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	163/451 (36%)
Sulf2	NP_001239508.1	AslA	76..>420	CDD:225661	144/349 (41%)
		G6S	76..418	CDD:293766	143/347 (41%)
		DUF3740	573..699	CDD:289325
		ALP_like	<787..836	CDD:304875
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847536
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840