DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30059 and sulf2

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001005661.1	Gene:	sulf2 / 448151	XenbaseID:	XB-GENE-950465	Length:	875	Species:	Xenopus tropicalis

Alignment Length:	489	Identity:	171/489 - (34%)
Similarity:	239/489 - (48%)	Gaps:	77/489 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PNILLILSDDQDVELRGMFPMEHTIEMLGFGGALFHNAYTPSPICCPARTSLLTGMYAHNHGTRN 88
            |||:|:|:|||||||..|..|..|..::..||..|.||:..:|:|||:|:|:|||.|.|||.|..
Frog    45 PNIILVLTDDQDVELGSMQVMNKTKRIMEQGGTHFINAFVTTPMCCPSRSSILTGKYVHNHNTYT 109

  Fly    89 NSVSGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLNQYWGAGDVPKGWNNFYGLHGNSRYY 153
            |:.:  |..|.|:...|.......|...||.|.|.|||||:|.|. .||.||..:.||..|||:|
Frog   110 NNEN--CSSPSWQAQHETHTFSVYLNNTGYRTAFFGKYLNEYNGT-YVPPGWKEWVGLVKNSRFY 171

  Fly   154 NYTL-----RENTGNVHYESTYLSDLLRDRAADFLRNATQ--SSEPFFAMVAPPAAHEPFTPAPR 211
            ||||     :|..| ..|...||:||:.:.:.:|.|.:.:  ...|...:::..|.|.|...||:
Frog   172 NYTLCRNGIKEKHG-FDYAQDYLTDLITNNSINFFRTSKKIYPHRPVLMVLSHVAPHGPEDSAPQ 235

  Fly   212 HEGVFSHIEALRTPSFNQV-KQDKHWLVR---AARRLPNETINTIDTYFQKRWETLLAVDELVVT 272
            :..:|.:.....|||:|.. ..||||::|   ..:.:..|..|.:.   ::|.:||::||..:..
Frog   236 YSQMFPNASQHITPSYNYAPNPDKHWIMRYTGPMKPIHMEFTNMLQ---RRRLQTLMSVDSSMEM 297

  Fly   273 LMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVPLLIRGPGIAPESHIDTAVS 337
            :..:|.:|..:||||||||:|:|||:|||.....|..|||.||.||..||||.:...|.....|.
Frog   298 IYNMLVETGEVENTYIIYTADHGYHIGQFGLVKGKSMPYEFDIRVPFYIRGPNVDAGSLNPHIVL 362

  Fly   338 LVDLAPTILAWADIDTPSYMDGQSFHELLLNKRRRVPFFERSLLIEYWGEGTLATFNPECPWPEK 402
            .:|||||||..|.:|.|..|||:|..: ||:..|.|..|.....::.|.:..|.         |:
Frog   363 NIDLAPTILDIAGLDIPPEMDGKSILK-LLDTERPVNRFHIHKKVKVWRDSFLV---------ER 417

  Fly   403 DRLAQCTPAADCHCQDAWNNTYACLRNIRHREDRIYCEFRDNENFLEAYDLQLDPFQMTNIAYDL 467
            .:|        .|.:|:               |::..:   .||||..|....|..|
Frog   418 GKL--------LHKRDS---------------DKVDAQ---EENFLPKYQRVKDLCQ-------- 448

  Fly   468 LPIERALYSLRLKNL---TQC----SG----HSC 490
                ||.|....:.|   .||    ||    |.|
Frog   449 ----RAEYQTACEQLGQKWQCVEDPSGKLRLHKC 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	161/453 (36%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	161/450 (36%)
sulf2	NP_001005661.1	G6S	44..386	CDD:293766	141/347 (41%)
		DUF3740	535..672	CDD:372181
		ALP_like	<755..804	CDD:390042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1273622at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010