Protein Alignment CG30059 and ARSB

DIOPT Version :10

• Sequence 1: NP_610872.1
• Gene: CG30059 / 246425
• FlyBaseID: FBgn0260475
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_000037.2
• Gene: ARSB / 411
• HGNCID: 714
• Length: 533
• Species: Homo sapiens
• Alignment Length: 507
• Identity: 117/507 - (23%)
• Similarity: 190/507 - (37%)
• Gaps: 143/507 - (28%)

  Fly     2 ITLAPLIVLVLACLGNTA-SEKLPNILLILSDD---QDVELRGMFPMEHTIEMLGFGGALFHNAY 62
            :.|..|::|:||..|:.| :.:.|:::.:|:||   .||...|.......::.|..||.|..|.|
Human    22 VVLPLLLLLLLAPPGSGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYY 86

  Fly    63 TPSPICCPARTSLLTGMYAHNHGTRNNSV---SGGCYGPHWRRALEPRALPYILQQHGYNTFFGG 124
            | .|:|.|:|:.||||.|....|.::..:   ...|.      .|:.:.||.:|::.||.|...|
Human    87 T-QPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCV------PLDEKLLPQLLKEAGYTTHMVG 144

  Fly   125 KYLNQYWGAG-------DVPKGWNNFYG-LHGNSRYYNY---TL-------------REN----T 161
            |     |..|       ...:|::.::| |.|:..||::   ||             |:.    |
Human   145 K-----WHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVAT 204

  Fly   162 GNVHYESTYLSDLLRDRAADFLRNATQSSEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRTPS 226
            |   |::.|.:::...||...:.| ....:|.|..:|..:.|||. ..|.        |.|:...
Human   205 G---YKNMYSTNIFTKRAIALITN-HPPEKPLFLYLALQSVHEPL-QVPE--------EYLKPYD 256

  Fly   227 FNQVKQDKHWLVRAARRLPNETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYIIYT 291
            |.|.|...|:....:                       .:||.|..:...|..:....||..|::
Human   257 FIQDKNRHHYAGMVS-----------------------LMDEAVGNVTAALKSSGLWNNTVFIFS 298

  Fly   292 SDNGYH------------------------VGQFAQPFDKRQPYETD--INV----PLLI---RG 323
            :|||..                        ||..|.|..|::..:..  |::    |.|:   ||
Human   299 TDNGGQTLAGGNNWPLRGRKWSLWEGGVRGVGFVASPLLKQKGVKNRELIHISDWLPTLVKLARG 363

  Fly   324 --PGIAPESHIDT--AVSLVDLAPTILAWADIDTPSYMDGQSFHELLLNKRRRVPFFERSLLIEY 384
              .|..|....|.  .:|....:|.|....:|| |:::|...     ..:....|..:.|.|.||
Human   364 HTNGTKPLDGFDVWKTISEGSPSPRIELLHNID-PNFVDSSP-----CPRNSMAPAKDDSSLPEY 422

  Fly   385 ------------WGEGTLATFNPEC----PWPEKDRLAQCTPAADCHCQDAW 420
                        .|...|.|..|.|    |.|.:..::: .|::|...:..|
Human   423 SAFNTSVHAAIRHGNWKLLTGYPGCGYWFPPPSQYNVSE-IPSSDPPTKTLW 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	110/484 (23%)
ARSB	NP_000037.2	4-S	45..488	CDD:293753	110/484 (23%)