Protein Alignment CG30059 and ARSA

DIOPT Version :10

• Sequence 1: NP_610872.1
• Gene: CG30059 / 246425
• FlyBaseID: FBgn0260475
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_000478.3
• Gene: ARSA / 410
• HGNCID: 713
• Length: 509
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 130/516 - (25%)
• Similarity: 179/516 - (34%)
• Gaps: 143/516 - (27%)

  Fly    10 LVLACLGNTASEKLPNILLILSDDQDVELRGMF--PMEHT--IEMLGFGGALFHNAYTPSPICCP 70
            |:||.....|..:.|||:||.:||......|.:  |...|  ::.|..||..|.:.|.|..:|.|
Human     9 LLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTP 73

  Fly    71 ARTSLLT-------GMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLN 128
            :|.:|||       |||.   |....|..||.       .||...:..:|...||.|...||
Human    74 SRAALLTGRLPVRMGMYP---GVLVPSSRGGL-------PLEEVTVAEVLAARGYLTGMAGK--- 125

  Fly   129 QYWGAGDVP--------KGWNNFYGL---HGNSRYYNYT--------------------LRENTG 162
              |..|..|        :|::.|.|:   |......|.|                    |..|.
Human   126 --WHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANL- 187

  Fly   163 NVHYESTYLSDL---LRDRAADFLRNATQSSEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRT 224
            :|..:..:|..|   ....|.|.:.:|.:...|||...|....|.|         .||      .
Human   188 SVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP---------QFS------G 237

  Fly   225 PSFNQVKQDKHWLVRAARRLPNETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYII 289
            .||.:         |:.|              ....::|:.:|..|.|||..:.|...||.|.:|
Human   238 QSFAE---------RSGR--------------GPFGDSLMELDAAVGTLMTAIGDLGLLEETLVI 279

  Fly   290 YTSDNGYHVGQFAQ-------PFDKRQPYETDINVPLLIRGPG-IAPESHIDTAVSLVDLAPTIL 346
            :|:|||....:.::       ...|...||..:..|.|...|| |||....:.|.|| ||.||:.
Human   280 FTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSL-DLLPTLA 343

  Fly   347 AWADIDTPSY-MDGQSFHELLL---NKRRRVPFFERSLLIEYWGEGTLATFNPECPW-----PEK 402
            |.|....|:. :||.....|||   ...|:..||..|...|..|...:.|...:..:     ...
Human   344 ALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHS 408

  Fly   403 DRLAQCTPAADCHCQDAWNNTYACLRNIRHREDRIYCEFRDNENFLEAYDLQLDPFQMTNI 463
            |..|.  ||  ||...:..         .|....:             |||..||.:..|:
Human   409 DTTAD--PA--CHASSSLT---------AHEPPLL-------------YDLSKDPGENYNL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	126/502 (25%)
ARSA	NP_000478.3	ARSA	22..505	CDD:293777	126/503 (25%)