DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30059 and Arsk

DIOPT Version :9

Sequence 1:	NP_610872.1	Gene:	CG30059 / 246425	FlyBaseID:	FBgn0260475	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001041382.1	Gene:	Arsk / 365619	RGDID:	1310182	Length:	563	Species:	Rattus norvegicus

Alignment Length:	535	Identity:	132/535 - (24%)
Similarity:	214/535 - (40%)	Gaps:	132/535 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MITLAPLIVLVLACLG---NTASEKL-----PNILLILSDDQDVELRGMFPMEHTIEMLGF---- 53
            |:.|...:::.||.:.   .|..::|     ||::|:.||..|..|  .|.....:..|.|
  Rat     1 MLLLLVSVIVALALVAPAPETQEKRLQVAQAPNVVLVASDSFDGRL--TFQPGSQVVKLPFINFM 63

  Fly    54 --GGALFHNAYTPSPICCPARTSLLTGMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPY--ILQ 114
              .|..|.||||.||||||:|.::.:|::.|...:.||.           :.|:|....:  :::
  Rat    64 RARGTTFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNF-----------KGLDPNYTTWMDVME 117

  Fly   115 QHGYNTFFGGK--YLNQYWGAGDVPKGWNNFYGLHGNSRYYNYTLRENTGNVHYESTYLSDLL-- 175
            :|||.|...||  |.:.:....:..:.|         :|...:.||:       |...:.:|:
  Rat   118 KHGYQTQKFGKLDYSSGHHSISNRVEAW---------TRDVAFLLRQ-------EGRPIINLIPD 166

  Fly   176 -------------RDRAADFLRNATQSSEPFFAMVA--------PPAAHEPFTPAPRHEGVFSHI 219
                         .|:|..:||. ..|::||...:.        .|::.|.|..:..|..::
  Rat   167 KNRRRVMDKDWQNTDKAIAWLRQ-VNSTKPFVLYLGLNLPHPYPSPSSGENFGSSTFHTSLY--- 227

  Fly   220 EALRTPSFNQVKQDKHWLVRA----------------ARRLPNETINTIDTYFQKRWETLLAVDE 268
             .|...:::.:|..| ||..:                .:...||..|....|:....||...:.|
  Rat   228 -WLEKVAYDAIKIPK-WLALSEMHPVDYYSSYTKNCTGKFTENEIKNIRAFYYAMCAETDAMLGE 290

  Fly   269 LVVTLMGVLNDTQSLENTYIIYTSDNGYHVGQFAQPFDKRQPYETDINVPLLIRGPGIAPESHID 333
            :::    .|:....|:.|.:|||||:|....:..| |.|...||...:||:|:.||||.....:.
  Rat   291 IIL----ALHKLNLLQKTIVIYTSDHGEMAMEHRQ-FYKMSMYEASAHVPILMMGPGIKANLQVP 350

  Fly   334 TAVSLVDLAPTILAWADIDTPSYMDGQSFHELLLNKRRRVPFFERSLLIEYWGEGTLATFNPECP 398
            :.|||||:.||:|..|.|..|..:.|.|...|..|.......|.              ..:|  |
  Rat   351 SLVSLVDIYPTMLDIAGIPLPLNLSGYSLLPLSSNTSANDQAFR--------------VHHP--P 399

  Fly   399 WPEKDRLAQCTPAADCHCQDAWNNTYACLRNIRHREDRIYCEFRDNENFL-EAYDLQLDPFQMTN 462
            |          ..::.|..:|..:|| .||..:.:    |..:.|..... :.:||.|||.::||
  Rat   400 W----------ILSEFHGCNANASTY-MLRTGQWK----YIAYSDGTLVQPQLFDLSLDPDELTN 449

  Fly   463 IAYDLLPIERALYSL 477
            ||.:...|   .|||
  Rat   450 IATEFPEI---TYSL 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30059	NP_610872.1	G6S	24..467	CDD:293766	122/492 (25%)
CG30059	NP_610872.1	AslA	24..464	CDD:225661	120/489 (25%)
Arsk	NP_001041382.1	ARSK	32..445	CDD:293781	117/483 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830